Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR2 | P21802 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 4/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.31 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
| ▸ | LCK | P06239 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | PDE4A | P27815 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30615194 | 0.83 | NQO2 (0.38) | KDM4EHSD17B10ALDH1A1MEN1KMT2A | |
| SCHEMBL29091666 | 0.83 | NQO2 (0.38) | KDM4EHSD17B10ALDH1A1MEN1KMT2A | |
| SCHEMBL29091596 | 0.79 | ALDH1A1 (0.34) | KDM4EALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL29091650 | 0.78 | KMT2A (0.50) | KDM4EMAPK1HSD17B10ALDH1A1MEN1 | |
| SCHEMBL29091614 | 0.73 | ALDH1A1 (0.36) | FGFR2KDM4EMAPK1HSD17B10FGFR1 | |
| SCHEMBL17527769 | 0.72 | L3MBTL1 (0.48) | FGFR2KDM4EMAPK1HSD17B10ALDH1A1 | |
| SCHEMBL24711958 | 0.70 | NQO2 (0.31) | — | |
| SCHEMBL29118912 | 0.70 | MAPT (0.32) | KDM4EMAPTLMNA | |
| SCHEMBL423475 | 0.69 | ALDH1A1 (0.46) | KDM4EHSD17B10ALOX5ALDH1A1ESR1 | |
| SCHEMBL28038952 | 0.69 | ALDH1A1 (0.46) | KDM4EHSD17B10ALOX5ALDH1A1ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116925100-A | Substituted thiophenoquinolinone compound and preparation method and application thereof | 深圳信立泰药业股份有限公司 | 2023-10-24 | — | — | CN | disclosed |