SCHEMBL29092148

SCHEMBL29092148

Nc1cc(Br)cc(-c2ccccc2-c2ccc(-c3ccccc3)cc2)c1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 1/20 0.45
ALDH1A1 P00352 4/20 0.45
HSD17B10 Q99714 3/20 0.45
MAPK1 P28482 2/20 0.45
CYP3A4 P08684 1/20 0.45
TAAR1 Q96RJ0 1/20 0.45
TDP1 Q9NUW8 1/20 0.45
AKR1C3 P42330 1/20 0.38
AKR1C2 P52895 1/20 0.38
AKR1C1 Q04828 1/20 0.38
ABL1 P00519 1/20 0.37
ABCB1 P08183 1/20 0.37
BCR P11274 1/20 0.37
ACHE P22303 1/20 0.36
MEN1 O00255 2/20 0.36
LMNA P02545 2/20 0.36
MAPT P10636 2/20 0.36
HTT P42858 2/20 0.36
KMT2A Q03164 2/20 0.36
KDM4E B2RXH2 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL99667 0.86 MAOA (0.54) MAOAALDH1A1HSD17B10MAPK1CYP3A4
SCHEMBL3523310 0.82 ALDH1A1 (0.54) ALDH1A1HSD17B10MAPK1TDP1AKR1C3
SCHEMBL13642473 0.77 ALDH1A1 (0.48) MAOAALDH1A1MAPK1AKR1C3AKR1C2
SCHEMBL30597431 0.76 ALDH1A1 (0.52) MAOAALDH1A1HSD17B10MAPK1CYP3A4
SCHEMBL25301802 0.75 HSD17B10 (0.79) MAOAALDH1A1HSD17B10MAPK1CYP3A4
SCHEMBL15705955 0.75 ALDH1A1 (0.79) ALDH1A1HSD17B10MAPK1TDP1MAPT
SCHEMBL28164997 0.75 HSD17B10 (0.79) MAOAALDH1A1HSD17B10MAPK1CYP3A4
SCHEMBL30416624 0.75 HSD17B10 (0.79) MAOAALDH1A1HSD17B10MAPK1CYP3A4
SCHEMBL28459830 0.74 ALDH1A1 (0.56) MAOAALDH1A1HSD17B10MAPK1CYP3A4
SCHEMBL28459829 0.74 HSD17B10 (0.56) MAOAALDH1A1HSD17B10MAPK1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108218722-B Novel compound and organic light emitting device comprising the same 东进世美肯株式会社 2023-10-27 CN disclosed