Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.46 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.46 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.46 |
| ▸ | BACE1 | P56817 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
| ▸ | ABL1 | P00519 | 1/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.41 |
| ▸ | BCR | P11274 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13642473 | 0.85 | ALDH1A1 (0.48) | ALDH1A1MAPK1AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL24200897 | 0.84 | ALDH1A1 (0.48) | ALDH1A1MAPK1AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL2278862 | 0.83 | ALDH1A1 (0.52) | ALDH1A1MAPK1BACE1HSD17B10HPGD | |
| SCHEMBL24716100 | 0.82 | ALDH1A1 (0.41) | ALDH1A1MAPK1AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL29092148 | 0.82 | MAOA (0.45) | ALDH1A1MAPK1AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL1562747 | 0.81 | ALDH1A1 (0.60) | ALDH1A1MAPK1AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL4142770 | 0.81 | ALDH1A1 (0.50) | ALDH1A1MAPK1BACE1HSD17B10HPGD | |
| SCHEMBL28199592 | 0.81 | ALDH1A1 (0.58) | ALDH1A1MAPK1AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL12996631 | 0.79 | ALDH1A1 (0.57) | ALDH1A1MAPK1AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL29410298 | 0.79 | ALDH1A1 (0.74) | ALDH1A1MAPK1BACE1HSD17B10HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109415354-A | Charge transport material, compound, delayed fluorescence material, and organic light-emitting element | 九州有机光材股份有限公司 | 2019-03-01 | — | — | CN | disclosed |
| US-7858794-B2 | Tetrahydroquinoline derivatives | N.V. ORGANON (NL) | 2010-12-28 | — | — | US | disclosed |
| US-20070116982-A1 | Host material for organic electroluminescent element and organic electroluminescent element | IDEMITSU KOSAN CO., LTD. (JP) | 2007-05-24 | — | — | US | disclosed |
| EP-1708547-A1 | HOST MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT AND ORGANIC ELECTROLUMINESCENT ELEMENT | IDEMITSU KOSAN CO., LTD. (JP) | 2006-10-04 | — | — | EP | disclosed |
| US-20060142334-A1 | Tetrahydroquinoline derivatives | MERCK SHARP & DOHME B.V. (NL) | 2006-06-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060142334-A1 | Tetrahydroquinoline derivatives | GNRHR, KCNH3, HCAR3 | ALDH1A1 1133/4885MAPK1 3862/4885AKR1C3 22/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.