Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 17/20 | 0.80 |
| ▸ | MAOA | P21397 | 15/20 | 0.80 |
| ▸ | CA12 | O43570 | 1/20 | 0.69 |
| ▸ | CA1 | P00915 | 1/20 | 0.69 |
| ▸ | CA2 | P00918 | 1/20 | 0.69 |
| ▸ | CA4 | P22748 | 1/20 | 0.69 |
| ▸ | CA5A | P35218 | 1/20 | 0.69 |
| ▸ | CA7 | P43166 | 1/20 | 0.69 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.69 |
| ▸ | ACHE | P22303 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29966607 | 1.00 | MAOB (0.80) | MAOBMAOACA12CA1CA2 | |
| SCHEMBL16562212 | 0.81 | MEN1 (0.64) | MAOBMAOACA12CA1CA2 | |
| SCHEMBL29828846 | 0.79 | MRGPRX4 (0.69) | MAOBMAOACA12CA1CA2 | |
| SCHEMBL7214701 | 0.79 | MRGPRX4 (0.69) | MAOBMAOACA12CA1CA2 | |
| SCHEMBL28078087 | 0.78 | MAOB (0.67) | MAOBMAOACA12CA1CA2 | |
| SCHEMBL7373528 | 0.78 | KDM4E (0.62) | MAOBMAOACA12CA1CA2 | |
| SCHEMBL28776653 | 0.78 | KDM4E (0.62) | MAOBMAOACA12CA1CA2 | |
| SCHEMBL9350122 | 0.78 | MAOB (0.72) | MAOBMAOACA12CA1CA2 | |
| SCHEMBL16554259 | 0.77 | MAOA (0.52) | MAOBMAOACA12CA1CA2 | |
| SCHEMBL10519865 | 0.77 | KDM4E (0.60) | MAOBMAOACA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116917280-A | Tetrahydronaphthalene compound, preparation method thereof and application thereof in medicine | 江苏恒瑞医药股份有限公司 | 2023-10-20 | — | — | CN | disclosed |