SCHEMBL29092245

SCHEMBL29092245

Clc1ccc(-n2nnc(I)c2I)cc1

nearest known ligand 0.45

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
NOTUM Q6P988 4/20 0.45
PTGS2 P35354 3/20 0.44
MAPT P10636 2/20 0.43
LMNA P02545 1/20 0.42
HSD17B10 Q99714 1/20 0.42
IDO1 P14902 1/20 0.41
TDO2 P48775 1/20 0.41
RAB9A P51151 2/20 0.40
MEN1 O00255 1/20 0.40
NPC1 O15118 1/20 0.40
TP53 P04637 1/20 0.40
KMT2A Q03164 1/20 0.40
FLT3 P36888 1/20 0.38
ALDH1A1 P00352 1/20 0.38
HTT P42858 1/20 0.38
F2 P00734 1/20 0.37
KDM4E B2RXH2 1/20 0.36
CYP1A2 P05177 1/20 0.36
CYP2C19 P33261 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29092869 0.80 NPC1 (0.44) MAPTLMNARAB9AMEN1NPC1
SCHEMBL29092634 0.80 ALDH1A1 (0.43) NOTUMPTGS2MAPTLMNARAB9A
SCHEMBL29092087 0.79 SMN1; SMN2 (0.44) MAPTLMNAIDO1TDO2RAB9A
SCHEMBL30584635 0.78 IDO1 (0.49) NOTUMMAPTLMNAIDO1TDO2
SCHEMBL29092867 0.78 IDO1 (0.49) NOTUMMAPTLMNAIDO1TDO2
SCHEMBL29092054 0.77 SMN1; SMN2 (0.42) NOTUMMAPTLMNARAB9AMEN1
SCHEMBL29092092 0.76 ALDH1A1 (0.44) PTGS2MAPTLMNARAB9AALDH1A1
SCHEMBL29092553 0.76 IDO1 (0.46) NOTUMMAPTIDO1TDO2TP53
SCHEMBL29092094 0.76 MAPT (0.48) NOTUMPTGS2MAPTRAB9AALDH1A1
SCHEMBL29092629 0.69 KCNN4 (0.44) NOTUMMEN1TP53KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116751172-A Synthesis method of diiodinated 1,2, 3-triazole compound 海南师范大学 2023-09-15 CN disclosed