SCHEMBL30584635

SCHEMBL30584635

Clc1cccc(-n2nnc(I)c2I)c1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 2/20 0.49
TDO2 P48775 1/20 0.49
NOTUM Q6P988 2/20 0.44
FLT3 P36888 2/20 0.43
POLB P06746 1/20 0.43
LMNA P02545 2/20 0.42
HTT P42858 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
ALDH1A1 P00352 2/20 0.41
MGLL Q99685 1/20 0.41
FGFR1 P11362 1/20 0.41
HPGD P15428 1/20 0.40
PKM P14618 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
GSK3B P49841 1/20 0.40
NPC1 O15118 1/20 0.40
RAB9A P51151 1/20 0.40
ATM Q13315 1/20 0.40
MAPT P10636 1/20 0.40
MPO P05164 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29092867 1.00 IDO1 (0.49) IDO1TDO2NOTUMFLT3POLB
SCHEMBL30584640 0.79 ALDH1A1 (0.53) IDO1TDO2POLBLMNAL3MBTL1
SCHEMBL29092100 0.79 MGLL (0.40) ALDH1A1MGLLGSK3B
SCHEMBL30584646 0.79 MGLL (0.40) ALDH1A1MGLLGSK3B
SCHEMBL29092128 0.79 ALDH1A1 (0.53) IDO1TDO2POLBLMNAL3MBTL1
SCHEMBL29092245 0.78 NOTUM (0.45) IDO1TDO2NOTUMFLT3LMNA
SCHEMBL29092087 0.77 SMN1; SMN2 (0.44) IDO1TDO2POLBLMNAHTT
SCHEMBL30584636 0.76 CYP1A2 (0.55) NOTUMPOLBLMNAHTTL3MBTL1
SCHEMBL29092095 0.76 CYP1A2 (0.55) NOTUMPOLBLMNAHTTL3MBTL1
SCHEMBL15554478 0.71 IDO1 (0.40) IDO1TDO2NOTUMFLT3POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116751172-A Synthesis method of diiodinated 1,2, 3-triazole compound 海南师范大学 2023-09-15 CN disclosed