SCHEMBL29092869

SCHEMBL29092869

Brc1ccc(-n2nnc(I)c2I)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 3/20 0.44
RAB9A P51151 3/20 0.44
ALDH1A1 P00352 3/20 0.36
TSHR P16473 2/20 0.36
CA1 P00915 6/20 0.35
CA2 P00918 6/20 0.35
CA4 P22748 6/20 0.35
CA9 Q16790 6/20 0.35
KMT2A Q03164 3/20 0.34
LMNA P02545 2/20 0.34
PKM P14618 1/20 0.34
MEN1 O00255 2/20 0.33
GLA P06280 1/20 0.33
NFKB1 P19838 1/20 0.33
NFKB2 Q00653 1/20 0.33
RELA Q04206 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
FAAH O00519 1/20 0.32
MGLL Q99685 1/20 0.32
SLC5A1 P13866 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29092245 0.80 NOTUM (0.45) NPC1RAB9AALDH1A1KMT2ALMNA
SCHEMBL29092634 0.80 ALDH1A1 (0.43) NPC1RAB9AALDH1A1TSHRCA1
SCHEMBL29092087 0.79 SMN1; SMN2 (0.44) NPC1RAB9AALDH1A1TSHRKMT2A
SCHEMBL30584646 0.78 MGLL (0.40) ALDH1A1CA1CA2CA9KMT2A
SCHEMBL29092100 0.78 MGLL (0.40) ALDH1A1CA1CA2CA9KMT2A
SCHEMBL29092054 0.77 SMN1; SMN2 (0.42) NPC1RAB9AALDH1A1KMT2ALMNA
SCHEMBL29092553 0.76 IDO1 (0.46) ALDH1A1CYP2A6MAPT
SCHEMBL29092094 0.76 MAPT (0.48) RAB9AALDH1A1CA9GAAMAPT
SCHEMBL29092092 0.76 ALDH1A1 (0.44) RAB9AALDH1A1TSHRLMNASMN1; SMN2
SCHEMBL29092063 0.69 KCNN4 (0.38) NPC1RAB9AALDH1A1MGLLSLC5A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116751172-A Synthesis method of diiodinated 1,2, 3-triazole compound 海南师范大学 2023-09-15 CN disclosed