SCHEMBL29093069

SCHEMBL29093069

Cc1cc(C)c(C2(N)C=CC=CC2N)cn1

nearest known ligand 0.37

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
UHRF1 Q96T88 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29092669 0.85
SCHEMBL30615659 0.85
SCHEMBL29092229 0.83 NNMT (0.38)
SCHEMBL28497606 0.74 ADRA2A (0.30)
SCHEMBL30615674 0.74 UHRF1 (0.36) UHRF1
SCHEMBL30615633 0.73 SIRT3 (0.33)
SCHEMBL30615430 0.73 HDAC4 (0.34)
SCHEMBL30615413 0.71
SCHEMBL30615610 0.70 P2RX7 (0.30)
SCHEMBL30615613 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111868037-B Fused cyclic urea derivatives as CRHR2 antagonists 拉夸里亚创药株式会社 2023-10-13 CN disclosed