Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2B | P29275 | 5/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.34 |
| ▸ | PDE4A | P27815 | 2/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.34 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.34 |
| ▸ | CNR2 | P34972 | 4/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29093824 | 0.92 | SYK (0.33) | ADORA2BADORA2APDE4APDE4BPDE4C | |
| SCHEMBL29093821 | 0.79 | KMT2A (0.43) | ADORA2BADORA2APDE4APDE4BPDE4C | |
| SCHEMBL29094003 | 0.76 | ADORA2A (0.33) | ADORA2BADORA2APDE4APDE4BPDE4C | |
| SCHEMBL29093834 | 0.76 | TLR8 (0.39) | ADORA2BCNR2ALDH1A1 | |
| SCHEMBL29093827 | 0.75 | BTK (0.41) | ADORA2BADORA2APDE4APDE4BPDE4C | |
| SCHEMBL29093826 | 0.75 | MEN1 (0.38) | ADORA2BADORA2APDE4APDE4BPDE4C | |
| SCHEMBL29093823 | 0.75 | NCOA1 (0.34) | ADORA2BADORA2APDE4APDE4BPDE4C | |
| SCHEMBL29093825 | 0.71 | ALDH1A1 (0.35) | ADORA2BADORA2APDE4APDE4BPDE4C | |
| SCHEMBL29094009 | 0.69 | KMO (0.40) | ADORA2BADORA2APDE4APDE4BPDE4C | |
| SCHEMBL29093852 | 0.69 | HTR2A (0.35) | ADORA2BADORA2APDE4APDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115572300-A | Synthesis method of sulfonamide substituted polycyclic quinazolinone compound | 江苏理工学院 | 2023-01-06 | — | — | CN | disclosed |