Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 12/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29093818 | 0.84 | LMNA (0.33) | TLR8LMNAADORA2B | |
| SCHEMBL29093824 | 0.84 | SYK (0.33) | KMT2AALDH1A1KDM4EGLAHPGD | |
| SCHEMBL29094008 | 0.78 | TLR8 (0.37) | TLR8SMN1; SMN2ALDH1A1KDM4EGLA | |
| SCHEMBL29094002 | 0.76 | PGR (0.38) | TLR8KMT2ASMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL29093854 | 0.76 | ADORA2B (0.34) | CNR2ALDH1A1ADORA2B | |
| SCHEMBL29093823 | 0.76 | NCOA1 (0.34) | CNR2ADORA2B | |
| SCHEMBL29093826 | 0.76 | MEN1 (0.38) | CNR2KMT2ASMN1; SMN2LMNAADORA2B | |
| SCHEMBL29093821 | 0.74 | KMT2A (0.43) | CNR2KMT2ASMN1; SMN2BRD4ADORA2B | |
| SCHEMBL29093861 | 0.74 | BTK (0.40) | TLR8KMT2ASMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL29094003 | 0.71 | ADORA2A (0.33) | CNR2KMT2ASMN1; SMN2ALDH1A1BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115572300-A | Synthesis method of sulfonamide substituted polycyclic quinazolinone compound | 江苏理工学院 | 2023-01-06 | — | — | CN | disclosed |