Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3A | P49840 | 2/20 | 0.39 |
| ▸ | GSK3B | P49841 | 2/20 | 0.39 |
| ▸ | KCNA5 | P22460 | 4/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.35 |
| ▸ | DAO | P14920 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | CMA1 | P23946 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | MMP1 | P03956 | 1/20 | 0.33 |
| ▸ | MMP9 | P14780 | 1/20 | 0.33 |
| ▸ | MMP13 | P45452 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2914544 | 0.88 | GSK3A (0.41) | GSK3AGSK3BKCNA5HRH3SIGMAR1 | |
| SCHEMBL2916485 | 0.78 | CYP3A4 (0.44) | HRH3SIGMAR1OPRM1OPRL1ALDH1A1 | |
| SCHEMBL2942975 | 0.77 | SIGMAR1 (0.48) | SIGMAR1OPRM1OPRL1MEN1TSHR | |
| SCHEMBL14447691 | 0.75 | EP300 (0.37) | DAOALDH1A1 | |
| SCHEMBL13849465 | 0.74 | CYP3A4 (0.39) | HRH3OPRM1OPRL1ALDH1A1MEN1 | |
| SCHEMBL2913300 | 0.74 | GHSR (0.40) | HRH3OPRM1OPRL1ALDH1A1MEN1 | |
| SCHEMBL14448672 | 0.73 | MCHR1 (0.40) | GSK3AGSK3BKCNA5OPRM1ALDH1A1 | |
| SCHEMBL2911536 | 0.73 | PTGS1 (0.37) | ALDH1A1KMT2AMMP1MMP13 | |
| SCHEMBL13849464 | 0.73 | CYP3A4 (0.38) | HRH3OPRM1OPRL1ALDH1A1MEN1 | |
| SCHEMBL2917139 | 0.73 | MMP1 (0.35) | ALDH1A1MEN1TSHRKMT2AMMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1763606-B1 | METHOD FOR COLORING TEXTILE SUBSTRATES, AQUEOUS PRETREATMENT BATHS, AND USE THEREOF FOR THE PRETREATMENT OF TEXTILE SUBSTRATES | BASF SE (DE) | 2010-09-01 | — | — | EP | disclosed |
| EP-1979355-B1 | SPIRO IMIDAZOLE DERIVATIVES AS PPAR MODULATORS | IRM LLC (BM) | 2010-08-18 | — | — | EP | disclosed |
| US-20090137610-A1 | SPIRO IMIDOZOLE DERIVATIVES AS PPAR MODULATORS | IRM LLC (BM) | 2009-05-28 | — | — | US | disclosed |
| US-20090137610-A1 | SPIRO IMIDOZOLE DERIVATIVES AS PPAR MODULATORS | IRM LLC (BM) | 2009-05-28 | — | — | US | disclosed |
| US-20090137610-A1 | SPIRO IMIDOZOLE DERIVATIVES AS PPAR MODULATORS | IRM LLC (BM) | 2009-05-28 | — | — | US | disclosed |
| EP-1979355-A1 | SPIRO IMIDAZOLE DERIVATIVES AS PPAR MODULATORS | IRM LLC (BM) | 2008-10-15 | — | — | EP | disclosed |
| EP-1781743-B1 | WATER-SOLUBLE PRODUCTS HARDENING WITH RADIATION AND USE THEREOF | BASF AG (DE) | 2008-01-02 | — | — | EP | disclosed |
| WO-2007087448-A1 | SPIRO IMIDAZOLE DERIVATIVES AS PPAR MODULATORS | IRM LLC (BM) | 2007-08-02 | — | — | WO | disclosed |
| WO-2007087448-A1 | SPIRO IMIDAZOLE DERIVATIVES AS PPAR MODULATORS | IRM LLC (BM) | 2007-08-02 | — | — | WO | disclosed |
| EP-1763606-A1 | METHOD FOR COLORING TEXTILE SUBSTRATES, AQUEOUS PRETREATMENT BATHS, AND USE THEREOF FOR THE PRETREATMENT OF TEXTILE SUBSTRATES | BASF AKTIENGESELLSCHAFT (DE) | 2007-03-21 | — | — | EP | disclosed |
| WO-2006000384-A1 | METHOD FOR COLORING TEXTILE SUBSTRATES, AQUEOUS PRETREATMENT BATHS, AND USE THEREOF FOR THE PRETREATMENT OF TEXTILE SUBSTRATES | BASF AKTIENGESELLSCHAFT (DE) | 2006-01-05 | — | — | WO | disclosed |
| EP-0937730-B1 | Process for preparing silylated carboxylic acid amides | WACKER CHEMIE GMBH (DE) | 2000-08-30 | — | — | EP | disclosed |
| EP-0937730-A2 | Process for preparing silylated carboxylic acid amides | Wacker Siltronic Gesellschaft für Halbleitermaterialien Aktiengesellschaft (DE) | 1999-08-25 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090137610-A1 | SPIRO IMIDOZOLE DERIVATIVES AS PPAR MODULATORS | PPARD, PPARG, PPARA | GSK3A 1785/4885GSK3B 1550/4885KCNA5 3133/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.