Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFD | P00746 | 1/20 | 0.52 |
| ▸ | NAMPT | P43490 | 5/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 2/20 | 0.37 |
| ▸ | GLS | O94925 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.36 |
| ▸ | ACACB | O00763 | 2/20 | 0.35 |
| ▸ | ACACA | Q13085 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CCKBR | P32239 | 1/20 | 0.35 |
| ▸ | CTSK | P43235 | 1/20 | 0.34 |
| ▸ | SCD | O00767 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29095062 | 0.86 | CFD (0.70) | CFDNAMPT | |
| SCHEMBL21455345 | 0.83 | CFD (0.59) | CFDNAMPTHDAC1BRD4GLS | |
| SCHEMBL21455344 | 0.82 | CFD (0.47) | CFDNAMPTHDAC1BRD4GLS | |
| SCHEMBL21455335 | 0.79 | PPID (0.45) | CFDNAMPTBRD4GLSCYP3A4 | |
| SCHEMBL21561820 | 0.76 | NAMPT (0.43) | CFDNAMPTBRD4GLSCYP3A4 | |
| SCHEMBL24299792 | 0.69 | NAMPT (0.48) | NAMPTHDAC1BRD4GLSCYP3A4 | |
| SCHEMBL21455332 | 0.69 | CFD (1.00) | CFD | |
| SCHEMBL21455336 | 0.68 | CFD (0.79) | CFD | |
| SCHEMBL301717 | 0.67 | PRMT6 (0.56) | NAMPTHDAC1BRD4GLSCYP3A4 | |
| SCHEMBL18664426 | 0.67 | HDAC1 (0.60) | HDAC1BRD4GLSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117164499-A | Substituted benzofurans, benzopyrroles, benzothiophenes and structurally related complement inhibitors | 拜奥克里斯特制药公司 | 2023-12-05 | — | — | CN | disclosed |
| CN-112272553-B | Substituted benzofurans, benzopyrroles, benzothiophenes and structurally related complement inhibitors | 拜奥克里斯特制药公司 | 2023-09-22 | — | — | CN | disclosed |