Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMEM97 | Q5BJF2 | 6/20 | 0.56 |
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.56 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.56 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.56 |
| ▸ | DRD4 | P21917 | 1/20 | 0.56 |
| ▸ | HRH1 | P35367 | 1/20 | 0.56 |
| ▸ | HTR2B | P41595 | 1/20 | 0.56 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.50 |
| ▸ | BRS3 | P32247 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | OGA | O60502 | 1/20 | 0.40 |
| ▸ | PIK3CB | P42338 | 4/20 | 0.39 |
| ▸ | PNMT | P11086 | 1/20 | 0.39 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.39 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2913307 | 0.84 | TMEM97 (0.60) | TMEM97SIGMAR1ADRA2AADRA2BDRD4 | |
| SCHEMBL2915724 | 0.80 | KMT2A (0.48) | TMEM97SIGMAR1ADRA2AADRA2BDRD4 | |
| SCHEMBL2912116 | 0.79 | TMEM97 (0.52) | TMEM97SIGMAR1ADRA2AADRA2BDRD4 | |
| SCHEMBL2912121 | 0.79 | TMEM97 (0.52) | TMEM97SIGMAR1ADRA2AADRA2BDRD4 | |
| SCHEMBL2913559 | 0.72 | MEN1 (0.57) | TMEM97SIGMAR1ADRA2AADRA2BDRD4 | |
| SCHEMBL2110621 | 0.72 | TMEM97 (0.48) | TMEM97SIGMAR1ADRA2AADRA2BDRD4 | |
| SCHEMBL17984887 | 0.72 | MEN1 (0.56) | TMEM97SIGMAR1ADRA2AADRA2BDRD4 | |
| SCHEMBL19537615 | 0.72 | SIGMAR1 (1.00) | TMEM97SIGMAR1ADRA2AADRA2BDRD4 | |
| SCHEMBL19521557 | 0.72 | SIGMAR1 (0.90) | TMEM97SIGMAR1ADRA2AADRA2BDRD4 | |
| SCHEMBL5774088 | 0.71 | MEN1 (0.55) | BRS3MEN1NPC1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2789338-A2 | Condensed pyridine derivate and use thereof | Takeda Pharmaceutical Company Limited (JP) | 2014-10-15 | — | — | EP | disclosed |
| US-20100266504-A1 | CONDENSED PYRIDINE DERIVATIVE AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-10-21 | — | — | US | disclosed |
| EP-2216023-A1 | CONDENSED PYRIDINE DERIVATIVE AND USE THEREOF | Takeda Pharmaceutical Company Limited (JP) | 2010-08-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100266504-A1 | CONDENSED PYRIDINE DERIVATIVE AND USE THEREOF | HTR2C, HTR5A, HTR3C | TMEM97 2223/4885SIGMAR1 2779/4885ADRA2A 576/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.