SCHEMBL290956

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL289817	0.82	HCAR2 (0.49)	KDM4EGAAHCAR2KMT2AMEN1
	SCHEMBL15173675	0.80	HCAR2 (0.53)	KDM4EHCAR2SMN1; SMN2KMT2AMEN1
	SCHEMBL1116700	0.78	ULK1 (0.53)	KDM4EGAAHCAR2HDAC1HDAC6
	SCHEMBL26673292	0.77	HCAR2 (0.50)	KDM4EHCAR2KMT2AMEN1TSHR
	SCHEMBL8947223	0.77	MAPK1 (0.60)	KDM4EGAASMN1; SMN2KMT2AMEN1
	SCHEMBL30640411	0.77	HCAR2 (0.50)	KDM4EHCAR2KMT2AMEN1TSHR
	SCHEMBL10923544	0.77	HCAR2 (0.46)	KDM4EGAAHCAR2SMN1; SMN2HSD17B10
	SCHEMBL19472394	0.76	KMT2A (0.63)	KDM4EGAASMN1; SMN2KMT2AMEN1
	SCHEMBL290548	0.75	GAA (0.46)	KDM4EGAASTAMBPSMN1; SMN2KMT2A
	SCHEMBL29779611	0.75	ATM (0.65)	KDM4EGAAHCAR2KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.