Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 11/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.46 |
| ▸ | PARP1 | P09874 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.40 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24470614 | 1.00 | USP30 (0.50) | USP30HDAC4HDAC6PARP1POLB | |
| SCHEMBL29095832 | 0.86 | ACHE (0.45) | POLBGAAKMT2A | |
| SCHEMBL30569447 | 0.85 | CASP3 (0.54) | USP30KMT2A | |
| SCHEMBL29104691 | 0.85 | SLC26A4 (0.46) | USP30KMT2A | |
| SCHEMBL29104664 | 0.85 | CASP3 (0.54) | USP30KMT2A | |
| SCHEMBL24470697 | 0.85 | CASP3 (0.54) | USP30KMT2A | |
| SCHEMBL24470692 | 0.85 | CASP3 (0.54) | USP30KMT2A | |
| SCHEMBL24470962 | 0.85 | SLC26A4 (0.46) | USP30KMT2A | |
| SCHEMBL30569383 | 0.85 | CASP3 (0.54) | USP30KMT2A | |
| SCHEMBL29104689 | 0.85 | SLC26A4 (0.46) | USP30KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116745283-A | Heterocyclic derivatives for the treatment of TRPM3 mediated disorders | 勒芬天主教大学 | 2023-09-12 | — | — | CN | disclosed |