Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | GPR35 | Q9HC97 | 4/20 | 0.36 |
| ▸ | LDHA | P00338 | 1/20 | 0.36 |
| ▸ | LDHB | P07195 | 1/20 | 0.36 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TTR | P02766 | 1/20 | 0.34 |
| ▸ | ALB | P02768 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | GABRP | O00591 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3758179 | 0.87 | CYP3A4 (0.45) | CYP3A4ACHEALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL21826384 | 0.79 | ALDH1A1 (0.44) | CYP3A4ACHEALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL22890471 | 0.79 | FFAR1 (0.39) | CYP3A4ACHEALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL29096098 | 0.78 | GPR35 (0.41) | CYP3A4ACHEALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL21937817 | 0.77 | POLB (0.44) | GPR35TTRALBMEN1KMT2A | |
| SCHEMBL16563793 | 0.76 | GPR35 (0.39) | ALDH1A1GPR35MRGPRX4TTRALB | |
| SCHEMBL29669953 | 0.75 | KDM4E (0.59) | GPR35MRGPRX4TTRALBKDM4E | |
| SCHEMBL951068 | 0.75 | KDM4E (0.59) | GPR35MRGPRX4TTRALBKDM4E | |
| SCHEMBL3125875 | 0.75 | TTR (0.40) | CYP3A4ALDH1A1SMN1; SMN2GPR35MRGPRX4 | |
| SCHEMBL8618720 | 0.75 | KDM4E (0.53) | CYP3A4ACHEALDH1A1MAPK1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116969954-B | Tricyclic fused heterocyclic compounds containing lactam and application thereof | 广东省农业科学院农业质量标准与监测技术研究所 | 2023-11-28 | — | — | CN | disclosed |
| CN-116969954-A | Tricyclic fused heterocyclic compounds containing lactam and application thereof | 广东省农业科学院农业质量标准与监测技术研究所 | 2023-10-31 | — | — | CN | disclosed |