SCHEMBL29096325

SCHEMBL29096325

CCOc1ccc(/C=C/C(=O)NN)cc1OC

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.68
HPGD P15428 4/20 0.68
MEN1 O00255 2/20 0.68
KMT2A Q03164 2/20 0.68
MAPT P10636 2/20 0.64
NPC1 O15118 2/20 0.64
RAB9A P51151 2/20 0.64
FDPS P14324 3/20 0.60
NFE2L2 Q16236 1/20 0.59
KDM4E B2RXH2 5/20 0.57
LMNA P02545 1/20 0.57
SNCA P37840 1/20 0.56
PTGES O14684 1/20 0.55
TOP2A P11388 1/20 0.54
SMN1; SMN2 Q16637 2/20 0.54
STAT1 P42224 1/20 0.54
PDE4A P27815 1/20 0.54
PDE4B Q07343 1/20 0.54
PDE4C Q08493 1/20 0.54
PDE4D Q08499 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15052622 0.89 NFE2L2 (0.69) ALDH1A1HPGDMEN1KMT2AMAPT
SCHEMBL15052623 0.89 NFE2L2 (0.69) ALDH1A1HPGDMEN1KMT2AMAPT
SCHEMBL9059283 0.87 APP (0.69) ALDH1A1HPGDMEN1KMT2ANPC1
SCHEMBL9059285 0.87 APP (0.69) ALDH1A1HPGDMEN1KMT2ANPC1
SCHEMBL30621449 0.86 PTGES (0.58) ALDH1A1HPGDMEN1KMT2ANPC1
SCHEMBL29096332 0.86 PTGES (0.58) ALDH1A1HPGDMEN1KMT2ANPC1
SCHEMBL29096333 0.84 ALDH1A1 (0.63) ALDH1A1HPGDMEN1KMT2AMAPT
SCHEMBL29096338 0.84 ALDH1A1 (0.63) ALDH1A1HPGDMEN1KMT2AMAPT
SCHEMBL29407074 0.84 ALDH1A1 (0.63) ALDH1A1HPGDMEN1KMT2AMAPT
SCHEMBL29096346 0.84 ALDH1A1 (0.62) ALDH1A1HPGDMEN1KMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117645560-A Ferulic acid derivative containing amide and preparation method and application thereof 贵州大学 2024-03-05 CN disclosed
CN-114195691-B Ferulic acid derivative containing amide and preparation method and application thereof 贵州大学 2023-10-20 CN disclosed
CN-114195691-A Amide-containing ferulic acid derivative and preparation method and application thereof 贵州大学 2022-03-18 CN disclosed