Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 2/20 | 0.51 |
| ▸ | MAOB | P27338 | 3/20 | 0.49 |
| ▸ | ERN1 | O75460 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | ALPL | P05186 | 1/20 | 0.43 |
| ▸ | ALPI | P09923 | 1/20 | 0.43 |
| ▸ | ALPG | P10696 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 3/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.40 |
| ▸ | TYR | P14679 | 1/20 | 0.40 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.40 |
| ▸ | MGLL | Q99685 | 1/20 | 0.40 |
| ▸ | APP | P05067 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.40 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.40 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29096545 | 1.00 | ADORA2A (0.51) | ADORA2AMAOBERN1MEN1KMT2A | |
| SCHEMBL29096557 | 0.84 | ERN1 (0.54) | MAOBERN1MEN1KMT2ACA2 | |
| SCHEMBL29096556 | 0.84 | ERN1 (0.54) | MAOBERN1MEN1KMT2ACA2 | |
| SCHEMBL29096551 | 0.83 | MEN1 (0.50) | MAOBERN1MEN1KMT2A | |
| SCHEMBL29096550 | 0.83 | MEN1 (0.50) | MAOBERN1MEN1KMT2A | |
| SCHEMBL29096521 | 0.83 | CA1 (0.43) | MAOBMEN1KMT2AALPGCA2 | |
| SCHEMBL29096524 | 0.83 | CA1 (0.43) | MAOBMEN1KMT2AALPGCA2 | |
| SCHEMBL29096536 | 0.81 | ALDH1A1 (0.47) | ADORA2AMAOBERN1MEN1KMT2A | |
| SCHEMBL29096547 | 0.80 | ADORA2A (0.41) | ADORA2AMAOBMEN1KMT2ACA2 | |
| SCHEMBL29096544 | 0.80 | ADORA2A (0.41) | ADORA2AMAOBMEN1KMT2ACA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116693552-A | Polycyclic dihydrobenzofuran compound and preparation method thereof | 浙江大学 | 2023-09-05 | — | — | CN | disclosed |