Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | KLK7 | P49862 | 4/20 | 0.42 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.38 |
| ▸ | STS | P08842 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | KLK5 | Q9Y337 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.37 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.37 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.37 |
| ▸ | GHSR | Q92847 | 1/20 | 0.36 |
| ▸ | CDC25B | P30305 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29096943 | 1.00 | USP2 (0.49) | USP2KLK7PARP1FKBP1ASTS | |
| SCHEMBL3815087 | 0.86 | KLK7 (0.50) | USP2KLK7PARP1STSKLK5 | |
| SCHEMBL8640234 | 0.86 | KLK7 (0.50) | USP2KLK7PARP1STSKLK5 | |
| SCHEMBL21837957 | 0.84 | USP2 (0.50) | USP2FKBP1ALMNAMEN1KMT2A | |
| SCHEMBL21837961 | 0.84 | USP2 (0.50) | USP2FKBP1ALMNAMEN1KMT2A | |
| SCHEMBL27032705 | 0.84 | USP2 (0.50) | USP2FKBP1ALMNAMEN1KMT2A | |
| SCHEMBL16050161 | 0.83 | USP2 (0.53) | USP2KLK7PARP1KLK5L3MBTL1 | |
| SCHEMBL16050314 | 0.83 | USP2 (0.53) | USP2KLK7PARP1KLK5L3MBTL1 | |
| SCHEMBL16050163 | 0.83 | USP2 (0.53) | USP2KLK7PARP1KLK5L3MBTL1 | |
| SCHEMBL8196492 | 0.81 | SMN1; SMN2 (0.44) | USP2KLK7PARP1STSKLK5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116981672-A | Macrocyclic compounds as CFTR modulators | 爱杜西亚药品有限公司 | 2023-10-31 | — | — | CN | disclosed |