Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | KLK7 | P49862 | 5/20 | 0.39 |
| ▸ | PPARG | P37231 | 3/20 | 0.39 |
| ▸ | PPARA | Q07869 | 3/20 | 0.39 |
| ▸ | PPARD | Q03181 | 2/20 | 0.38 |
| ▸ | STS | P08842 | 1/20 | 0.37 |
| ▸ | KLK5 | Q9Y337 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.36 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8640234 | 0.85 | KLK7 (0.50) | USP2KLK7STSKLK5MEN1 | |
| SCHEMBL3815087 | 0.85 | KLK7 (0.50) | USP2KLK7STSKLK5MEN1 | |
| SCHEMBL6371613 | 0.84 | USP2 (0.61) | SMN1; SMN2USP2NPC1RAB9ANPSR1 | |
| SCHEMBL6371611 | 0.84 | USP2 (0.61) | SMN1; SMN2USP2NPC1RAB9ANPSR1 | |
| SCHEMBL29096947 | 0.81 | USP2 (0.49) | USP2KLK7PPARASTSKLK5 | |
| SCHEMBL29096943 | 0.81 | USP2 (0.49) | USP2KLK7PPARASTSKLK5 | |
| SCHEMBL16578256 | 0.78 | ALDH1A1 (0.35) | SMN1; SMN2USP2MEN1KMT2APARP1 | |
| SCHEMBL16050161 | 0.78 | USP2 (0.53) | USP2KLK7KLK5MEN1KMT2A | |
| SCHEMBL16050163 | 0.78 | USP2 (0.53) | USP2KLK7KLK5MEN1KMT2A | |
| SCHEMBL16050314 | 0.78 | USP2 (0.53) | USP2KLK7KLK5MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6043278-A | FORMULATION COMPRISING MIXTURE OF BETA-LACTAM ANTIBIOTIC AND PERFLUOROLOWERALKYL DERIVATIVE OF AMINO ACID | ISIS INNOVATION LIMITED (GB) | 2000-03-28 | — | — | US | disclosed |