Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLK7 | P49862 | 9/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | KLK5 | Q9Y337 | 7/20 | 0.47 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.45 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.45 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.45 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.45 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.45 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.45 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.45 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.45 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.45 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.45 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.45 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.43 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.43 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | STS | P08842 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8640234 | 1.00 | KLK7 (0.50) | KLK7USP2KLK5PSEN1PSEN2 | |
| SCHEMBL29096947 | 0.86 | USP2 (0.49) | KLK7USP2KLK5NR1H2NR1H3 | |
| SCHEMBL29096943 | 0.86 | USP2 (0.49) | KLK7USP2KLK5NR1H2NR1H3 | |
| SCHEMBL8196492 | 0.85 | SMN1; SMN2 (0.44) | KLK7USP2KLK5PRSS1PRSS2 | |
| SCHEMBL16050161 | 0.82 | USP2 (0.53) | KLK7USP2KLK5PSEN1PSEN2 | |
| SCHEMBL16050314 | 0.82 | USP2 (0.53) | KLK7USP2KLK5PSEN1PSEN2 | |
| SCHEMBL16050163 | 0.82 | USP2 (0.53) | KLK7USP2KLK5PSEN1PSEN2 | |
| SCHEMBL7317628 | 0.82 | USP2 (0.67) | USP2PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL5704537 | 0.82 | USP2 (0.67) | USP2PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL27041465 | 0.81 | USP2 (0.46) | USP2PSEN1PSEN2APH1BNCSTN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090270499-A1 | Process for Synthesizing Atazanavir | OXYRANE (UK) LIMITED (UK) | 2009-10-29 | — | — | US | disclosed |
| US-20090270499-A1 | Process for Synthesizing Atazanavir | OXYRANE (UK) LIMITED (UK) | 2009-10-29 | — | — | US | disclosed |
| US-20090270499-A1 | Process for Synthesizing Atazanavir | OXYRANE (UK) LIMITED (UK) | 2009-10-29 | — | — | US | disclosed |
| WO-2009130534-A1 | PROCESS FOR SYNTHESIZING ATAZANAVIR | OXYRANE (PTY) LTD. (ZA) | 2009-10-29 | — | — | WO | disclosed |
| US-6906224-B2 | Process for producing α-aminoketones | AJINOMOTO CO., INC. (JP) | 2005-06-14 | — | — | US | disclosed |
| US-20040210089-A1 | Process for producing alpha-aminoketones | AJINOMOTO CO., INC. (JP) | 2004-10-21 | — | — | US | disclosed |
| US-6696571-B2 | REACTING A 3-OXAZOLIDIN-5-ONE DERIVATIVE WITH A HALOMETHYL LITHIUM AND THEN TREATING WITH AN ACID | AJINOMOTO CO., INC. (JP) | 2004-02-24 | — | — | US | disclosed |
| US-20030100796-A1 | Process for producing alpha-aminoketones | AJINOMOTO CO., INC. (JP) | 2003-05-29 | — | — | US | disclosed |
| US-6570039-B2 | Oxazolidine compounds as chemical intermediates | AJINOMOTO CO., INC. (JP) | 2003-05-27 | — | — | US | disclosed |
| US-20020035288-A1 | Process for producing alpha-aminoketones | AJINOMOTO CO., INC. (JP) | 2002-03-21 | — | — | US | disclosed |
| US-6043278-A | FORMULATION COMPRISING MIXTURE OF BETA-LACTAM ANTIBIOTIC AND PERFLUOROLOWERALKYL DERIVATIVE OF AMINO ACID | ISIS INNOVATION LIMITED (GB) | 2000-03-28 | — | — | US | disclosed |
| EP-0863753-A1 | PERFLUOROALKYL SUBSTITUTED METALLO-BETA-LACTAMASE INHIBITORS AND METHOD FOR THE PREPARATION OF TRIFLUOROMETHYLKETONE DERIVATIVES | ISIS INNOVATION LIMITED (GB) | 1998-09-16 | — | — | EP | disclosed |
| WO-1997019681-A1 | PERFLUOROALKYL SUBSTITUTED METALLO-BETA-LACTAMASE INHIBITORS AND METHOD FOR THE PREPARATION OF TRIFLUOROMETHYLKETONE DERIVATIVES | ISIS INNOVATION LIMITED (GB) | 1997-06-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040210089-A1 | Process for producing alpha-aminoketones | AAAS, BCKDK, KHK | KLK7 331/4885USP2 2237/4885KLK5 123/4885 |
| US-20020035288-A1 | Process for producing alpha-aminoketones | AAAS, BCKDK, KHK | KLK7 331/4885USP2 2237/4885KLK5 123/4885 |
| US-20030100796-A1 | Process for producing alpha-aminoketones | AAAS, BCKDK, KHK | KLK7 331/4885USP2 2237/4885KLK5 123/4885 |
| US-20090270499-A1 | Process for Synthesizing Atazanavir | SAMHD1, TYMS, COASY | KLK7 1879/4885USP2 3815/4885KLK5 1455/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.