Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 1/20 | 0.51 |
| ▸ | MAP3K7 | O43318 | 5/20 | 0.50 |
| ▸ | ALK | Q9UM73 | 3/20 | 0.50 |
| ▸ | MAP2K1 | Q02750 | 3/20 | 0.49 |
| ▸ | BRD4 | O60885 | 7/20 | 0.49 |
| ▸ | EGFR | P00533 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.47 |
| ▸ | SRC | P12931 | 1/20 | 0.47 |
| ▸ | SYK | P43405 | 1/20 | 0.47 |
| ▸ | CCNK | O75909 | 1/20 | 0.47 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.47 |
| ▸ | CDK2 | P24941 | 1/20 | 0.47 |
| ▸ | CCND3 | P30281 | 1/20 | 0.47 |
| ▸ | CDK9 | P50750 | 1/20 | 0.47 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29097555 | 0.87 | EGFR (0.54) | MAP3K7ALKEGFRSRC | |
| SCHEMBL29097716 | 0.86 | ALK (0.57) | MAP3K7ALKMAP2K1BRD4FGFR1 | |
| SCHEMBL30621972 | 0.86 | ALK (0.57) | MAP3K7ALKMAP2K1BRD4FGFR1 | |
| SCHEMBL31318206 | 0.82 | MAP3K7 (0.47) | SLC2A1MAP3K7ALKMAP2K1BRD4 | |
| SCHEMBL29097572 | 0.80 | MAP3K7 (0.47) | SLC2A1MAP3K7ALKMAP2K1BRD4 | |
| SCHEMBL29097550 | 0.79 | BRD4 (0.56) | MAP3K7ALKBRD4EGFRFGFR1 | |
| SCHEMBL29097567 | 0.77 | PDCD1 (0.33) | — | |
| SCHEMBL25068891 | 0.76 | ALK (0.68) | MAP3K7ALKMAP2K1BRD4EGFR | |
| SCHEMBL30621968 | 0.73 | EGFR (0.59) | MAP3K7ALKEGFRSRC | |
| SCHEMBL29097707 | 0.73 | EGFR (0.59) | MAP3K7ALKEGFRSRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116903592-A | Pyrimidine amine NUAK inhibitor and preparation method and application thereof | 特科罗生物科技(成都)有限公司 | 2023-10-20 | — | — | CN | disclosed |