Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 4/20 | 0.59 |
| ▸ | BPTF | Q12830 | 2/20 | 0.51 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.48 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | HTR2C | P28335 | 1/20 | 0.46 |
| ▸ | HTR2B | P41595 | 1/20 | 0.46 |
| ▸ | MELK | Q14680 | 1/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.41 |
| ▸ | AXL | P30530 | 2/20 | 0.41 |
| ▸ | TYRO3 | Q06418 | 2/20 | 0.41 |
| ▸ | MERTK | Q12866 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30199093 | 1.00 | PNMT (0.59) | PNMTBPTFSLC2A1HTR2AHTR2C | |
| SCHEMBL29098005 | 0.79 | PNMT (0.55) | PNMTBPTFSLC2A1HTR2AHTR2C | |
| SCHEMBL30200120 | 0.79 | PNMT (0.55) | PNMTBPTFSLC2A1HTR2AHTR2C | |
| SCHEMBL29587836 | 0.76 | PNMT (1.00) | PNMTHTR2AHTR2CHTR2BADRA2A | |
| SCHEMBL329775 | 0.76 | PNMT (1.00) | PNMTHTR2AHTR2CHTR2BADRA2A | |
| Hydrochloric Acid SCHEMBL1124954 | 0.75 | PNMT (0.96) | PNMTSLC2A1HTR2AHTR2CHTR2B | |
| SCHEMBL655463 | 0.73 | AXL (0.49) | BPTFAXLTYRO3MERTK | |
| SCHEMBL29097884 | 0.71 | TAS1R3 (0.46) | KMT2A | |
| SCHEMBL532012 | 0.69 | PNMT (0.85) | PNMTHTR2AHTR2CHTR2BADRA2A | |
| SCHEMBL13315765 | 0.69 | PNMT (0.55) | PNMTMELKADRA2AADRA2BADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115594669-A | Fused ring derivative and preparation method and medical application thereof | 深圳信立泰药业股份有限公司（CN） | 2023-01-13 | — | — | CN | disclosed |