Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 2/20 | 0.55 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.46 |
| ▸ | MELK | Q14680 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.42 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.42 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29098005 | 1.00 | PNMT (0.55) | PNMTSLC2A1MELKHTR2AHTR2C | |
| SCHEMBL29097883 | 0.79 | PNMT (0.59) | PNMTSLC2A1MELKHTR2AHTR2C | |
| SCHEMBL30199093 | 0.79 | PNMT (0.59) | PNMTSLC2A1MELKHTR2AHTR2C | |
| SCHEMBL18668932 | 0.78 | PNMT (0.50) | PNMTSLC2A1MELKITGB3PLA2G1B | |
| SCHEMBL2640999 | 0.76 | PNMT (0.50) | PNMTSLC2A1HTR2AHTR2CHTR2B | |
| SCHEMBL29097887 | 0.75 | PNMT (0.54) | PNMTSLC2A1HTR2AHTR2CHTR2B | |
| SCHEMBL29587836 | 0.73 | PNMT (1.00) | PNMTHTR2AHTR2CHTR2B | |
| SCHEMBL329775 | 0.73 | PNMT (1.00) | PNMTHTR2AHTR2CHTR2B | |
| SCHEMBL29097825 | 0.73 | ERCC1 (0.43) | HTR2CHTR2BMEN1KMT2A | |
| SCHEMBL18668939 | 0.73 | PNMT (0.45) | PNMTHTR2CHTR2BPLA2G1BATG4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115594669-B | Parallel ring derivative and preparation method and medical application thereof | 深圳信立泰药业股份有限公司 | 2024-11-05 | — | — | CN | disclosed |
| CN-115594669-A | Fused ring derivative and preparation method and medical application thereof | 深圳信立泰药业股份有限公司（CN） | 2023-01-13 | — | — | CN | disclosed |