Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.57 |
| ▸ | NPC1 | O15118 | 6/20 | 0.57 |
| ▸ | RAB9A | P51151 | 5/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | PKM | P14618 | 1/20 | 0.57 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 3/20 | 0.48 |
| ▸ | MAOA | P21397 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | ALPL | P05186 | 1/20 | 0.47 |
| ▸ | ALPI | P09923 | 1/20 | 0.47 |
| ▸ | ALPG | P10696 | 1/20 | 0.47 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.47 |
| ▸ | CRHBP | P24387 | 1/20 | 0.47 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3038749 | 0.82 | MAOB (0.58) | MAPTNPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL3038740 | 0.82 | MAOB (0.58) | MAPTNPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL6993037 | 0.81 | MAPT (0.62) | MAPTNPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL6993038 | 0.81 | MAPT (0.62) | MAPTNPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL3270436 | 0.79 | RAB9A (0.48) | MAPTNPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL28623353 | 0.78 | MAPT (0.41) | MAPTNPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL11097938 | 0.78 | NPC1 (0.47) | MAPTNPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL28379713 | 0.78 | ALDH1A1 (0.61) | MAPTALDH1A1LMNAPOLBKDM4E | |
| SCHEMBL11097937 | 0.78 | NPC1 (0.47) | MAPTNPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL30189480 | 0.77 | RAB9A (0.46) | MAPTNPC1RAB9AALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116554056-A | Cyclohexane compound with multiple functional groups and preparation method thereof | 贵州医科大学 | 2023-08-08 | — | — | CN | disclosed |