Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | PANK3 | Q9H999 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.32 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5954700 | 0.76 | LMNA (0.42) | LMNAKMT2AMAPTNAPRTTRPV1 | |
| SCHEMBL1550807 | 0.75 | LMNA (0.41) | LMNAKMT2AMAPTNAPRTTRPV1 | |
| SCHEMBL1000276 | 0.72 | ALDH1A1 (0.40) | LMNAKMT2AMAPTTRPV1HTT | |
| SCHEMBL18106959 | 0.71 | LMNA (0.37) | LMNAKMT2A | |
| Lithium Ion SCHEMBL1550804 | 0.68 | LMNA (0.41) | LMNAKMT2AMAPTTRPV1HTT | |
| SCHEMBL15375598 | 0.68 | ALDH1A1 (0.40) | LMNAKMT2AMAPTHTTALDH1A1 | |
| SCHEMBL30549680 | 0.67 | ALDH1A1 (0.38) | LMNAKMT2AMAPTTRPV1HTT | |
| Hydrochloric Acid SCHEMBL31404963 | 0.66 | ALDH1A1 (0.39) | LMNAKMT2AMAPTHTTALDH1A1 | |
| SCHEMBL31292247 | 0.66 | LMNA (0.43) | LMNAKMT2AMAPTTRPV1SMN1; SMN2 | |
| SCHEMBL19185845 | 0.64 | LMNA (0.36) | LMNAKMT2AMAPTHTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111170991-B | Antiproliferative compounds and methods of synthesis thereof | 细胞基因公司 | 2023-10-31 | — | — | CN | disclosed |