Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | JMJD6 | Q6NYC1 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7515477 | 0.80 | JMJD6 (0.53) | KMT2ANPC1RAB9AMEN1POLB | |
| SCHEMBL26108944 | 0.75 | KMT2A (0.43) | KMT2ANPC1RAB9AMEN1POLB | |
| SCHEMBL30703365 | 0.74 | JMJD6 (0.48) | KMT2ANPC1RAB9AMEN1POLB | |
| SCHEMBL10133288 | 0.74 | ALDH1A1 (0.63) | KMT2ANPC1RAB9AMEN1POLB | |
| SCHEMBL1431340 | 0.74 | KMT2A (0.44) | KMT2ANPC1RAB9AMEN1POLB | |
| SCHEMBL25007588 | 0.74 | NPC1 (0.44) | KMT2ANPC1RAB9AMEN1POLB | |
| SCHEMBL9682529 | 0.74 | ALDH1A1 (0.67) | KMT2ANPC1RAB9AMEN1POLB | |
| SCHEMBL568799 | 0.73 | KMT2A (0.43) | KMT2ANPC1RAB9AMEN1POLB | |
| SCHEMBL20189189 | 0.73 | SCN4A (0.46) | KMT2ANPC1RAB9AMEN1POLB | |
| SCHEMBL24423465 | 0.73 | KMT2A (0.43) | KMT2ANPC1RAB9AMEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110709392-B | Isoquinoline as HPK1 inhibitor | 豪夫迈·罗氏有限公司 | 2023-09-29 | — | — | CN | disclosed |