Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.41 |
| ▸ | FABP3 | P05413 | 1/20 | 0.39 |
| ▸ | FABP4 | P15090 | 1/20 | 0.39 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29099825 | 0.83 | ADORA3 (0.42) | KMT2AADORA3KDM4EALDH1A1GAA | |
| SCHEMBL2186187 | 0.81 | KDM4E (0.60) | KMT2APOLBKDM4EALDH1A1GAA | |
| SCHEMBL5213888 | 0.75 | GPR3 (0.62) | KMT2APOLBKDM4EALDH1A1HPGD | |
| SCHEMBL29099831 | 0.74 | KDM4E (0.47) | KMT2AADORA3KDM4EALDH1A1GAA | |
| SCHEMBL29099859 | 0.73 | KDM4E (0.46) | KMT2AKDM4EALDH1A1GAAHPGD | |
| SCHEMBL28350758 | 0.72 | MAPT (0.43) | KMT2APOLBKDM4EALDH1A1HPGD | |
| SCHEMBL29099818 | 0.72 | USP2 (0.48) | KMT2APOLBKDM4EALDH1A1GAA | |
| SCHEMBL29539238 | 0.71 | KMT2A (0.56) | KMT2AADORA3KDM4EALDH1A1GAA | |
| SCHEMBL29099843 | 0.71 | KDM4E (0.44) | KMT2AADORA3KDM4EALDH1A1GAA | |
| SCHEMBL1415347 | 0.70 | KMT2A (0.55) | KMT2AKDM4EALDH1A1GAAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116969889-B | Preparation method of phenanthridine or chiral phenanthridine compound | 瑞博(杭州)医药科技有限公司 | 2024-03-26 | — | — | CN | disclosed |
| CN-116969889-A | Preparation method of phenanthridine or chiral phenanthridine compound | 瑞博(杭州)医药科技有限公司 | 2023-10-31 | — | — | CN | disclosed |