Known targets — ChEMBL curated mechanism
ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3CALCRLCHRM1CHRM2CHRM3F2RMAOAMAOBMAP2K1MAP2K2NTRK1NTRK2NTRK3OPRD1OPRK1OPRM1P2RY12PKLRSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASLC18A2SLC6A2SLC6A3TLR7TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8dacAdacBdacCfolAftsImrcAmrcBmrdApolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmB1rpmB2rpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmHrpmIrpmJrpmJ2rpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsR1rpsR2rpsSrpsTrpsUrpsZykgMykgO
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.43 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.42 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.42 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | TAS2R10 | Q9NYW0 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL27570806 | 0.98 | CYP1A2 (0.45) | CYP1A2KDM4EALDH1A1TDP1LMNA | |
| SCHEMBL330402 | 0.94 | CYP1A2 (0.49) | CYP1A2KDM4EALDH1A1TDP1LMNA | |
| SCHEMBL331081 | 0.94 | CYP1A2 (0.45) | CYP1A2KDM4EALDH1A1TDP1LMNA | |
| Sulfuric Acid SCHEMBL27570804 | 0.93 | CYP1A2 (0.42) | CYP1A2KDM4EALDH1A1TDP1LMNA | |
| Sulfuric Acid SCHEMBL782175 | 0.92 | CYP1A2 (0.44) | CYP1A2KDM4EALDH1A1TDP1LMNA | |
| Thiosulfuric Acid SCHEMBL8422607 | 0.92 | CYP1A2 (0.44) | CYP1A2KDM4EALDH1A1TDP1LMNA | |
| Ammonia Solution, Strong SCHEMBL27995410 | 0.92 | CYP1A2 (0.48) | CYP1A2KDM4EALDH1A1TDP1LMNA | |
| Sulfuric Acid SCHEMBL27810236 | 0.91 | CYP1A2 (0.43) | CYP1A2KDM4EALDH1A1TDP1LMNA | |
| Sulfuric Acid SCHEMBL10541168 | 0.91 | KDM4E (0.44) | CYP1A2KDM4EALDH1A1TDP1LMNA | |
| SCHEMBL330933 | 0.89 | TSHR (0.55) | CYP1A2KDM4EALDH1A1TDP1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021107047-A1 | METHOD FOR PRODUCING 4-(AMINOMETHYL)CYCLOHEXANE CARBOXYLIC ACID | 株式会社ＤＮＰファインケミカル | 2021-06-03 | — | — | WO | disclosed |
| EP-1781646-B1 | PROCESS FOR THE PREPARATION OF 11-(4-[2-(2-HYDROXYETHOXY)ETHYL]-1-PIPERAZINYL)DIBENZO[b,f][1,4]THIAZEPINE | SK HOLDINGS CO LTD (KR) | 2010-08-18 | — | — | EP | disclosed |
| US-7678902-B2 | Process for the preparation of 11-(4-[2-(2-hydroxyethoxy)ethyl]-1-piperazinyl)dibenzo[b,f][1,4]thiazepine | SK HOLDINGS CO., LTD. (KR) | 2010-03-16 | — | — | US | disclosed |
| EP-1781646-A4 | PROCESS FOR THE PREPARATION OF 11-(4-[2-(2-HYDROXYETHOXY)ETHYL]-I-PIPERAZINYL)DIBENZO[B,F][1,4]THIAZEPINE | SK HOLDINGS CO LTD (KR) | 2009-03-04 | — | — | EP | disclosed |
| US-20070225494-A1 | Process for the Preparation of 11-(4-[2-(2-Hydroxyethoxy)Ethyl]-I-Piperazinyl)Dibenzo[b,f][I,4]Thiazepine | SK CORPORATION (KR) | 2007-09-27 | — | — | US | disclosed |
| EP-1781646-A1 | PROCESS FOR THE PREPARATION OF 11-(4-[2-(2-HYDROXYETHOXY)ETHYL]-I-PIPERAZINYL)DIBENZO[B,F][1,4]THIAZEPINE | SK Corporation (KR) | 2007-05-09 | — | — | EP | disclosed |
| WO-2006001619-A1 | PROCESS FOR THE PREPARATION OF 11-(4-[2-(2-HYDROXYETHOXY)ETHYL]-I-PIPERAZINYL)DIB ENZO[b,f][l,4]THIAZEPINE | SK CORPORATION (KR) | 2006-01-05 | — | — | WO | disclosed |
| US-4891168-A | Process for producing steroid derivatives | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1990-01-02 | — | — | US | disclosed |
| EP-0261656-A1 | A process for producing steroid derivatives | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1988-03-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070225494-A1 | Process for the Preparation of 11-(4-[2-(2-Hydroxyethoxy)Ethyl]-I-Piperazinyl)Dibenzo[b,f][I,4]Thiazepine | TALDO1, QDPR, HDHD5 | CYP1A2 136/4885KDM4E 775/4885ALDH1A1 299/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.