Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 3/20 | 0.41 |
| ▸ | METAP1 | P53582 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | REN | P00797 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | GMNN | O75496 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25348570 | 1.00 | METAP2 (0.41) | METAP2METAP1TP53RENKDM4E | |
| SCHEMBL25348565 | 1.00 | METAP2 (0.41) | METAP2METAP1TP53RENKDM4E | |
| Hydrochloric Acid SCHEMBL7277822 | 0.94 | KDM4E (0.45) | METAP2METAP1TP53RENKDM4E | |
| SCHEMBL9437467 | 0.88 | REN (0.43) | METAP2METAP1TP53RENKDM4E | |
| SCHEMBL9800611 | 0.88 | REN (0.43) | METAP2METAP1TP53RENKDM4E | |
| SCHEMBL7436156 | 0.88 | REN (0.43) | METAP2METAP1TP53RENKDM4E | |
| SCHEMBL1368930 | 0.88 | REN (0.43) | METAP2METAP1TP53RENKDM4E | |
| SCHEMBL8915949 | 0.86 | REN (0.42) | METAP2METAP1TP53RENKDM4E | |
| SCHEMBL9676548 | 0.84 | REN (0.43) | METAP2METAP1TP53RENKDM4E | |
| SCHEMBL7282042 | 0.80 | REN (0.37) | METAP2METAP1TP53RENKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116783204-A | Modulators of cystic fibrosis transmembrane conductance regulator | 弗特克斯药品有限公司 | 2023-09-19 | — | — | CN | disclosed |