Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 6/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2910062 | 1.00 | LMNA (0.55) | LMNAPLA2G4AMAPTTDP1MEN1 | |
| SCHEMBL30410952 | 1.00 | LMNA (0.55) | LMNAPLA2G4AMAPTTDP1MEN1 | |
| SCHEMBL9779564 | 0.84 | MAPT (0.67) | LMNAMAPTTDP1MEN1KMT2A | |
| SCHEMBL9779567 | 0.84 | MAPT (0.67) | LMNAMAPTTDP1MEN1KMT2A | |
| SCHEMBL7166946 | 0.83 | ALDH5A1 (0.63) | LMNAPLA2G4AMAPTTDP1MEN1 | |
| SCHEMBL2785445 | 0.83 | ALDH5A1 (0.63) | LMNAPLA2G4AMAPTTDP1MEN1 | |
| SCHEMBL10797509 | 0.83 | MAPT (0.64) | LMNAPLA2G4AMAPTTDP1MEN1 | |
| SCHEMBL10780080 | 0.83 | MAPT (0.64) | LMNAPLA2G4AMAPTTDP1MEN1 | |
| SCHEMBL2785447 | 0.83 | ALDH5A1 (0.63) | LMNAPLA2G4AMAPTTDP1MEN1 | |
| SCHEMBL8237371 | 0.82 | TTR (0.52) | LMNAMAPTTDP1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116103917-A | Anti-water-drenching wear-resistant canvas fabric and preparation method thereof | 王霆 | 2023-05-12 | — | — | CN | claimed |
| CN-116103917-A | Anti-water-drenching wear-resistant canvas fabric and preparation method thereof | 王霆 | 2023-05-12 | — | — | CN | disclosed |
| CN-116103917-A | Anti-water-drenching wear-resistant canvas fabric and preparation method thereof | 王霆 | 2023-05-12 | — | — | CN | disclosed |
| EP-1937650-B1 | HETEROCYCLIC COMPOUNDS | S BIO PTE LTD (SG) | 2011-06-15 | — | — | EP | disclosed |
| US-7795250-B2 | Indole derivatives as antiviral agents | ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P ANGELETTI SPA (IT) | 2010-09-14 | — | — | US | disclosed |
| EP-1758857-B1 | INDOLE DERIVATIVES AS ANTIVIRAL AGENTS | ANGELETTI P IST RICHERCHE BIO (IT) | 2010-08-18 | — | — | EP | disclosed |
| US-20080261944-A1 | Indole Derivatives as Antiviral Agents | ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P ANGELETTI SPA (IT) | 2008-10-23 | — | — | US | disclosed |
| WO-2007030080-A1 | HETEROCYCLIC COMPOUNDS | S*BIO PTE LTD (SG) | 2007-03-15 | — | — | WO | disclosed |
| EP-1758857-A1 | INDOLE DERIVATIVES AS ANTIVIRAL AGENTS | Istituto di Richerche di Biologia Molecolare P. Angeletti S.p.A. (IT) | 2007-03-07 | — | — | EP | disclosed |
| WO-2006029912-A1 | INDOLE DERIVATIVES AS ANTIVIRAL AGENTS | ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P. ANGELETTI SPA (IT) | 2006-03-23 | — | — | WO | disclosed |
| CN-1036064-C | Benzene derivatives having NGF production-promoting activity | SANKYO CO (JP) | 1997-10-08 | — | — | CN | disclosed |
| US-5643925-A | COGNITION ACTIVATORS AND NERVE GROWTH FACTORS | SANKYO COMPANY, LIMITED (JP) | 1997-07-01 | — | — | US | disclosed |
| US-5614521-A | NERVE GROWTH FACTOR | SANKYO COMPANY, LIMITED (JP) | 1997-03-25 | — | — | US | disclosed |
| EP-0501656-B1 | New benzene derivatives having (NGF) production-promoting activity | SANKYO CO (JP) | 1997-01-22 | — | — | EP | disclosed |
| CN-1064273-A | The new NGF that has generates the active benzene derivative of promotion | SANKYO CO (JP) | 1992-09-09 | — | — | CN | disclosed |
| EP-0501656-A2 | New benzene derivatives having (NGF) production-promoting activity | Sankyo Company Limited (JP) | 1992-09-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080261944-A1 | Indole Derivatives as Antiviral Agents | IDO1, IDO2, IRF3 | LMNA 3219/4885PLA2G4A 2325/4885MAPT 3543/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.