SCHEMBL29100712

SCHEMBL29100712

CCCCCC[C@H](NC(=O)[C@H](CCC(=O)OC(C)(C)C)NC(=O)OCc1ccccc1)C(=O)OC(C)(C)C

nearest known ligand 0.55

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
SIRT2 Q8IXJ6 14/20 0.55
SIRT1 Q96EB6 9/20 0.55
SIRT3 Q9NTG7 6/20 0.55
CTSL P07711 1/20 0.55
CTSS P25774 1/20 0.55
MEN1 O00255 1/20 0.54
ALDH1A1 P00352 1/20 0.54
HPGD P15428 1/20 0.54
KMT2A Q03164 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29100713 1.00 SIRT2 (0.55) SIRT2SIRT1SIRT3CTSLCTSS
SCHEMBL29100662 0.94 SIRT2 (0.61) SIRT2SIRT1SIRT3CTSLCTSS
SCHEMBL29100660 0.94 SIRT2 (0.61) SIRT2SIRT1SIRT3CTSLCTSS
SCHEMBL7904398 0.92 CTSK (0.51) CTSLCTSS
SCHEMBL29750243 0.92 MEN1 (0.58) SIRT2SIRT1SIRT3MEN1ALDH1A1
SCHEMBL10389689 0.90 SIRT2 (0.62) SIRT2SIRT1SIRT3CTSLCTSS
SCHEMBL26896562 0.89 CTSL (0.60) SIRT2SIRT1SIRT3CTSLCTSS
SCHEMBL30902868 0.88 CTSK (0.51) CTSLCTSS
SCHEMBL13570900 0.88 SYK (0.55) CTSLCTSSALDH1A1
SCHEMBL9819558 0.88 SYK (0.55) CTSLCTSSALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250375544-A1 DUAL MODE RADIOTRACER AND -THERAPEUTICS UNIV MUENCHEN TECH (DE) 2025-12-11 US disclosed
EP-4271422-A1 DUAL MODE RADIOTRACER AND -THERAPEUTICS Technische Universität München (DE) 2023-11-08 EP disclosed
CN-116981486-A Dual mode radiotracer and therapeutic agent 慕尼黑工业大学 2023-10-31 CN disclosed
WO-2022144467-A1 DUAL MODE RADIOTRACER AND -THERAPEUTICS Technische Universität München (DE) 2022-07-07 WO disclosed
EP-4023250-A1 DUAL MODE RADIOTRACER AND -THERAPEUTICS Technische Universität München (DE) 2022-07-06 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250375544-A1 DUAL MODE RADIOTRACER AND -THERAPEUTICS MAN2B1, GBA1, SSTR1 SIRT2 2417/4885SIRT1 1790/4885SIRT3 2513/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.