Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K1 | Q92918 | 12/20 | 0.51 |
| ▸ | ALK | Q9UM73 | 6/20 | 0.49 |
| ▸ | AXL | P30530 | 1/20 | 0.45 |
| ▸ | MET | P08581 | 2/20 | 0.44 |
| ▸ | INSR | P06213 | 2/20 | 0.44 |
| ▸ | IGF1R | P08069 | 2/20 | 0.44 |
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24716908 | 0.88 | MAP4K1 (0.53) | MAP4K1ALKAXLMET | |
| SCHEMBL24716364 | 0.87 | MAP4K1 (0.68) | MAP4K1ALKINSRIGF1R | |
| SCHEMBL24716306 | 0.85 | ALK (0.69) | ALKMETINSR | |
| SCHEMBL24716379 | 0.80 | MAP4K1 (0.74) | MAP4K1ALKMET | |
| SCHEMBL29102658 | 0.79 | MAP4K1 (0.52) | MAP4K1ALKAXLMET | |
| SCHEMBL24715910 | 0.77 | MAP4K1 (0.68) | MAP4K1ALKINSRIGF1REGFR | |
| SCHEMBL24715916 | 0.76 | MAP4K1 (0.71) | MAP4K1ALKMETINSRIGF1R | |
| SCHEMBL24716047 | 0.76 | MAP4K1 (0.54) | MAP4K1ALKAXLMET | |
| SCHEMBL24716012 | 0.75 | ALK (0.62) | MAP4K1ALKAXLMETINSR | |
| SCHEMBL24716307 | 0.75 | MAP4K1 (0.55) | MAP4K1ALKAXLMET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116848103-A | High activity HPK1 kinase inhibitors | 杭州阿诺生物医药科技有限公司 | 2023-10-03 | — | — | CN | disclosed |