Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 3/20 | 0.38 |
| ▸ | DRD4 | P21917 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 6/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | APAF1 | O14727 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.35 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 2/20 | 0.35 |
| ▸ | ESRRB | O95718 | 2/20 | 0.34 |
| ▸ | ESRRG | P62508 | 2/20 | 0.34 |
| ▸ | FPR2 | P25090 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29104005 | 1.00 | DRD2 (0.38) | DRD2DRD4MAPTGLAKMT2A | |
| SCHEMBL29104074 | 0.85 | MAPT (0.38) | DRD2DRD4MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL29104070 | 0.85 | MAPT (0.38) | DRD2DRD4MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL29104027 | 0.78 | AKR1C3 (0.38) | DRD2DRD4MAPTGLAKMT2A | |
| SCHEMBL29104024 | 0.78 | AKR1C3 (0.38) | DRD2DRD4MAPTGLAKMT2A | |
| SCHEMBL29104046 | 0.73 | NR1H2 (0.48) | MAPTKMT2AALDH1A1ESRRBESRRG | |
| SCHEMBL2116079 | 0.70 | MEN1 (0.49) | DRD4MAPTKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL28094591 | 0.69 | AKR1C3 (0.40) | DRD2DRD4MAPTKMT2ANPSR1 | |
| SCHEMBL29104082 | 0.67 | AKR1C3 (0.41) | DRD2DRD4MAPTKMT2ANPSR1 | |
| SCHEMBL29104065 | 0.66 | SLC6A2 (0.33) | DRD2DRD4MAPTKMT2ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117003755-A | Pyrazolopyridazinone derivatives, compositions and uses thereof | 北京伯汇生物技术有限公司 | 2023-11-07 | — | — | CN | disclosed |