Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 6/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 2/20 | 0.36 |
| ▸ | DRD4 | P21917 | 1/20 | 0.36 |
| ▸ | CNKSR1 | Q969H4 | 1/20 | 0.35 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29104027 | 1.00 | AKR1C3 (0.38) | AKR1C3MAPTALDH1A1GAAPOLB | |
| SCHEMBL29104070 | 0.82 | MAPT (0.38) | AKR1C3MAPTALDH1A1GAAPOLB | |
| SCHEMBL29104074 | 0.82 | MAPT (0.38) | AKR1C3MAPTALDH1A1GAAPOLB | |
| SCHEMBL29104005 | 0.78 | DRD2 (0.38) | AKR1C3MAPTALDH1A1GAAPOLB | |
| SCHEMBL29104010 | 0.78 | DRD2 (0.38) | AKR1C3MAPTALDH1A1GAAPOLB | |
| SCHEMBL29104026 | 0.69 | NR1H2 (0.51) | MAPTALDH1A1LMNA | |
| SCHEMBL29104080 | 0.66 | ADRB1 (0.44) | MAPTGAANPSR1 | |
| SCHEMBL2116079 | 0.66 | MEN1 (0.49) | MAPTALDH1A1SLC6A2SLC6A4DRD4 | |
| SCHEMBL26099880 | 0.65 | TRIM24 (0.38) | AKR1C3ALDH1A1GAASLC6A2SLC6A4 | |
| SCHEMBL26099884 | 0.65 | TRIM24 (0.38) | AKR1C3ALDH1A1GAASLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117003755-A | Pyrazolopyridazinone derivatives, compositions and uses thereof | 北京伯汇生物技术有限公司 | 2023-11-07 | — | — | CN | disclosed |