Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PHGDH | O43175 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | RAD52 | P43351 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14279690 | 0.84 | GAA (0.35) | PHGDHGAARAD52KMT2A | |
| SCHEMBL14279646 | 0.83 | GAA (0.42) | GAARAD52KMT2ASIGMAR1 | |
| SCHEMBL13197467 | 0.79 | SIGMAR1 (0.44) | GAARAD52KMT2ASIGMAR1 | |
| SCHEMBL28782784 | 0.76 | GAA (0.35) | GAARAD52KMT2ASIGMAR1 | |
| SCHEMBL31208861 | 0.76 | SOS1 (0.32) | PHGDHTSHR | |
| SCHEMBL2084825 | 0.74 | PHGDH (0.32) | PHGDH | |
| SCHEMBL4376672 | 0.73 | HCN1 (0.44) | SIGMAR1 | |
| SCHEMBL4124999 | 0.73 | KMT2A (0.44) | GAARAD52KMT2ASIGMAR1TSHR | |
| SCHEMBL4132978 | 0.71 | SIGMAR1 (0.44) | GAARAD52KMT2ASIGMAR1TSHR | |
| SCHEMBL22765711 | 0.71 | SIGMAR1 (0.30) | GAARAD52KMT2ASIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117003755-A | Pyrazolopyridazinone derivatives, compositions and uses thereof | 北京伯汇生物技术有限公司 | 2023-11-07 | — | — | CN | disclosed |