Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 8/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | RAD52 | P43351 | 1/20 | 0.42 |
| ▸ | MC4R | P32245 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4124999 | 0.85 | KMT2A (0.44) | SIGMAR1KMT2AALDH1A1MEN1CYP2C9 | |
| SCHEMBL4130873 | 0.81 | CYP2D6 (0.43) | SIGMAR1KMT2AALDH1A1MEN1CYP2C9 | |
| SCHEMBL27839716 | 0.79 | SIGMAR1 (0.46) | SIGMAR1KMT2AALDH1A1MEN1CYP2C9 | |
| Hydrochloric Acid SCHEMBL27820189 | 0.78 | SIGMAR1 (0.45) | SIGMAR1KMT2AALDH1A1MEN1CYP2C9 | |
| SCHEMBL4280380 | 0.77 | OPRM1 (0.47) | SIGMAR1KMT2AALDH1A1MEN1OPRM1 | |
| SCHEMBL4119403 | 0.77 | CARM1 (0.41) | SIGMAR1KMT2AGAARAD52MC4R | |
| SCHEMBL4374266 | 0.75 | OPRM1 (0.51) | SIGMAR1MC4ROPRM1 | |
| SCHEMBL14279693 | 0.74 | KMT2A (0.47) | SIGMAR1KMT2AALDH1A1MEN1CYP2C9 | |
| SCHEMBL4118117 | 0.72 | OPRM1 (0.45) | SIGMAR1KMT2AALDH1A1MEN1CYP2C9 | |
| SCHEMBL14279644 | 0.72 | GAA (0.55) | SIGMAR1KMT2AGAARAD52MC4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090253669-A1 | Substituted Sulfonamide Compounds | GRUENENTHAL GMBH (DE) | 2009-10-08 | — | — | US | disclosed |
| US-20090253669-A1 | Substituted Sulfonamide Compounds | GRUENENTHAL GMBH (DE) | 2009-10-08 | — | — | US | disclosed |
| US-20090253669-A1 | Substituted Sulfonamide Compounds | GRUENENTHAL GMBH (DE) | 2009-10-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090253669-A1 | Substituted Sulfonamide Compounds | SULT2A1, STS, SULT1A1 | SIGMAR1 1349/4885KMT2A 1309/4885ALDH1A1 863/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.