Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.37 |
| ▸ | BRPF1 | P55201 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | DRD2 | P14416 | 2/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.34 |
| ▸ | QRFPR | Q96P65 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.34 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.34 |
| ▸ | MAT2A | P31153 | 1/20 | 0.34 |
| ▸ | PROKR1 | Q8TCW9 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29104139 | 0.90 | MCHR1 (0.43) | MCHR1BRPF1MEN1KMT2ADRD2 | |
| SCHEMBL29104138 | 0.85 | RXFP1 (0.38) | RXFP1MEN1KMT2A | |
| SCHEMBL29104119 | 0.84 | MCL1 (0.43) | RXFP1BRPF1MEN1KMT2A | |
| SCHEMBL29104112 | 0.84 | HPGD (0.43) | RXFP1MCHR1BRPF1MEN1KMT2A | |
| SCHEMBL29104132 | 0.82 | DAO (0.42) | BRPF1MEN1KMT2ACYP2D6PROKR1 | |
| SCHEMBL29104152 | 0.82 | L3MBTL1 (0.45) | — | |
| SCHEMBL29104123 | 0.77 | MCHR1 (0.35) | RXFP1MCHR1BRPF1MEN1KMT2A | |
| SCHEMBL29104144 | 0.76 | MCHR1 (0.35) | MCHR1BRPF1KCNH2 | |
| SCHEMBL29104134 | 0.75 | BRD4 (0.38) | RXFP1 | |
| SCHEMBL22004117 | 0.75 | AHR (0.45) | AHRRXFP1MCHR1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117003738-A | Imidazole spiro compound and synthesis method thereof | 湘潭大学 | 2023-11-07 | — | — | CN | claimed |
| CN-117003738-A | Imidazole spiro compound and synthesis method thereof | 湘潭大学 | 2023-11-07 | — | — | CN | disclosed |