Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | PDE2A | O00408 | 1/20 | 0.39 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.39 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29104138 | 0.83 | RXFP1 (0.38) | KDM4EALDH1A1HPGDHSD17B10PDE2A | |
| SCHEMBL29104119 | 0.82 | MCL1 (0.43) | L3MBTL1HPGD | |
| SCHEMBL29104129 | 0.82 | AHR (0.40) | — | |
| SCHEMBL29104112 | 0.82 | HPGD (0.43) | KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL29104132 | 0.80 | DAO (0.42) | HSD17B10BRD4 | |
| SCHEMBL29104123 | 0.75 | MCHR1 (0.35) | KDM4EALDH1A1HSD17B10PDE2APDE3B | |
| SCHEMBL29104139 | 0.74 | MCHR1 (0.43) | L3MBTL1KDM4EALDH1A1HPGDBRD4 | |
| SCHEMBL29104144 | 0.74 | MCHR1 (0.35) | KDM4EALDH1A1HPGDHSD17B10MAOA | |
| SCHEMBL29104149 | 0.74 | MTNR1A (0.43) | MAPK1MTNR1A | |
| SCHEMBL318066 | 0.70 | MAPK1 (0.56) | ALDH1A1HPGDSMN1; SMN2MAPK1MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117003738-A | Imidazole spiro compound and synthesis method thereof | 湘潭大学 | 2023-11-07 | — | — | CN | claimed |
| CN-117003738-A | Imidazole spiro compound and synthesis method thereof | 湘潭大学 | 2023-11-07 | — | — | CN | disclosed |