Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 3/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.34 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.32 |
| ▸ | SRD5A1 | P18405 | 3/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | MCHR2 | Q969V1 | 1/20 | 0.32 |
| ▸ | PLK1 | P53350 | 1/20 | 0.32 |
| ▸ | PLK2 | Q9NYY3 | 1/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.32 |
| ▸ | PRKDC | P78527 | 1/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | TLR4 | O00206 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29104112 | 0.90 | HPGD (0.43) | MCHR1BRPF1SRD5A1PLK1PLK2 | |
| SCHEMBL29104123 | 0.85 | MCHR1 (0.35) | MCHR1BRPF1PIK3CAPRKDCMAOA | |
| SCHEMBL29104139 | 0.84 | MCHR1 (0.43) | MCHR1BRPF1SRD5A1KDM4EALDH1A1 | |
| SCHEMBL29104132 | 0.82 | DAO (0.42) | BRPF1HSD17B10 | |
| SCHEMBL29104138 | 0.77 | RXFP1 (0.38) | KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL29104129 | 0.76 | AHR (0.40) | MCHR1BRPF1KCNH2 | |
| SCHEMBL29104119 | 0.76 | MCL1 (0.43) | BRPF1SRD5A1HPGDTLR4 | |
| SCHEMBL29104152 | 0.74 | L3MBTL1 (0.45) | MAOAKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL29104142 | 0.73 | DRD2 (0.51) | ATMKDM4EALDH1A1 | |
| SCHEMBL29104131 | 0.71 | ALDH1A1 (0.32) | PIK3CAPRKDCMAOAALDH1A1TLR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117003738-A | Imidazole spiro compound and synthesis method thereof | 湘潭大学 | 2023-11-07 | — | — | CN | claimed |
| CN-117003738-A | Imidazole spiro compound and synthesis method thereof | 湘潭大学 | 2023-11-07 | — | — | CN | disclosed |