SCHEMBL29104337

SCHEMBL29104337

COc1cc(OC)c(COS(=O)(=O)C(F)(F)F)c(OC)c1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 1/20 0.40
CYP3A4 P08684 4/20 0.39
USP2 O75604 1/20 0.39
MAPK1 P28482 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
ERN1 O75460 1/20 0.39
CYP1A2 P05177 4/20 0.38
ALDH1A1 P00352 2/20 0.38
PTPN1 P18031 1/20 0.38
TAS2R14 Q9NYV8 1/20 0.36
ACHE P22303 1/20 0.36
CYP1A1 P04798 2/20 0.35
CYP1B1 Q16678 2/20 0.35
HTR2A P28223 1/20 0.35
HTR2C P28335 1/20 0.35
HTR2B P41595 1/20 0.35
CYP2C19 P33261 2/20 0.35
CYP2E1 P05181 1/20 0.34
CYP2C8 P10632 1/20 0.34
CYP2D6 P10635 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27772408 0.77 HSD17B10 (0.55) ALDH1A1HTR2A
SCHEMBL5679303 0.73 CA2 (0.61) CA2SMN1; SMN2
Phosphine SCHEMBL29104339 0.73 CYP1A2 (0.40) CA2CYP3A4USP2MAPK1SMN1; SMN2
SCHEMBL27772412 0.73 CA2 (0.53) CA2MAPK1SMN1; SMN2ALDH1A1
SCHEMBL5238331 0.73 HTR2A (0.33) HTR2AHTR2CHTR2B
Ammonia Solution, Strong SCHEMBL28500084 0.72 CA2 (0.59) CA2SMN1; SMN2
SCHEMBL20478039 0.72 IDO1 (0.53) CA2CYP1A2
SCHEMBL21472948 0.71 CA2 (0.42) CA2CYP3A4MAPK1CYP1A2CYP2C19
SCHEMBL1713657 0.71 ALDH1A1 (0.48) CA2CYP1A2ALDH1A1CYP1A1CYP1B1
SCHEMBL20478018 0.71 IDO1 (0.50) CA2SMN1; SMN2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116854552-A Polysubstituted olefin and preparation method thereof 苏州华道生物药业股份有限公司 2023-10-10 CN disclosed