Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A5 | Q9Y345 | 14/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.45 |
| ▸ | SLC26A4 | O43511 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.43 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.43 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24471016 | 1.00 | SLC6A5 (0.49) | SLC6A5LMNAHTTHDAC4HDAC6 | |
| SCHEMBL29713019 | 1.00 | SLC6A5 (0.49) | SLC6A5LMNAHTTHDAC4HDAC6 | |
| SCHEMBL29104702 | 1.00 | SLC6A5 (0.49) | SLC6A5LMNAHTTHDAC4HDAC6 | |
| SCHEMBL29712955 | 0.92 | LMNA (0.55) | SLC6A5LMNAHTTHDAC4HDAC6 | |
| SCHEMBL24470954 | 0.92 | LMNA (0.55) | SLC6A5LMNAHTTHDAC4HDAC6 | |
| SCHEMBL29104679 | 0.92 | LMNA (0.55) | SLC6A5LMNAHTTHDAC4HDAC6 | |
| SCHEMBL29104677 | 0.92 | LMNA (0.55) | SLC6A5LMNAHTTHDAC4HDAC6 | |
| SCHEMBL24470962 | 0.92 | SLC26A4 (0.46) | LMNAHTTUSP30SLC26A4KMT2A | |
| SCHEMBL29104691 | 0.92 | SLC26A4 (0.46) | LMNAHTTUSP30SLC26A4KMT2A | |
| SCHEMBL29104689 | 0.92 | SLC26A4 (0.46) | LMNAHTTUSP30SLC26A4KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116761796-A | Aryl derivatives for the treatment of TRPM3 mediated disorders | 勒芬天主教大学 | 2023-09-15 | — | — | CN | disclosed |