Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNQ2 | O43526 | 1/20 | 0.80 |
| ▸ | KCNQ4 | P56696 | 1/20 | 0.80 |
| ▸ | KCNQ5 | Q9NR82 | 1/20 | 0.80 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.63 |
| ▸ | MEN1 | O00255 | 4/20 | 0.63 |
| ▸ | PTGES | O14684 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.58 |
| ▸ | LMNA | P02545 | 4/20 | 0.58 |
| ▸ | HTT | P42858 | 4/20 | 0.57 |
| ▸ | GLA | P06280 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29105146 | 0.89 | KCNQ2 (0.68) | KCNQ2KCNQ4KCNQ5KMT2AMEN1 | |
| SCHEMBL29105142 | 0.83 | KCNQ2 (0.83) | KCNQ2KCNQ4KCNQ5KMT2AMEN1 | |
| SCHEMBL29105135 | 0.83 | KCNQ2 (0.74) | KCNQ2KCNQ4KCNQ5KMT2AMEN1 | |
| SCHEMBL4206740 | 0.78 | PKM (0.67) | KCNQ2KCNQ4KCNQ5KMT2AMEN1 | |
| SCHEMBL29105154 | 0.75 | KCNQ2 (0.76) | KCNQ2KCNQ4KCNQ5KMT2AMEN1 | |
| SCHEMBL14970817 | 0.72 | ALDH1A1 (0.81) | KCNQ2KCNQ4KCNQ5KMT2AMEN1 | |
| SCHEMBL4212339 | 0.72 | TP53 (0.67) | KCNQ2KCNQ4KCNQ5KMT2AMEN1 | |
| SCHEMBL4203649 | 0.72 | PTGES (0.62) | KMT2AMEN1PTGESLMNACYP3A4 | |
| SCHEMBL4206164 | 0.71 | ALDH1A1 (0.75) | KMT2AMEN1MAPK1L3MBTL1HPGD | |
| SCHEMBL29105141 | 0.71 | KCNQ2 (0.70) | KCNQ2KCNQ4KCNQ5KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116763781-A | Triazole derivative and preparation method and application thereof | 华东师范大学 | 2023-09-19 | — | — | CN | disclosed |