Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | XDH | P47989 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2907804 | 0.88 | XDH (0.39) | TSHRALDH1A1MAPK1KMT2AMEN1 | |
| SCHEMBL2915031 | 0.87 | MAPT (0.39) | MAPTHSD17B10TSHRALDH1A1MAPK1 | |
| SCHEMBL1530763 | 0.80 | AURKB (0.47) | MAPTHSD17B10TSHRALDH1A1MAPK1 | |
| SCHEMBL2913166 | 0.78 | XDH (0.38) | ALDH1A1MAPK1KMT2AMEN1RAB9A | |
| SCHEMBL2915057 | 0.78 | CRBN (0.39) | MAPTHSD17B10TSHRALDH1A1MAPK1 | |
| SCHEMBL2909532 | 0.78 | NR1H4 (0.39) | MAPTHSD17B10TSHRALDH1A1RAB9A | |
| SCHEMBL2913787 | 0.78 | KIF18A (0.39) | MAPTHSD17B10TSHR | |
| SCHEMBL2907824 | 0.78 | MAPT (0.39) | MAPTHSD17B10TSHRALDH1A1RAB9A | |
| SCHEMBL2913182 | 0.77 | NR1H4 (0.36) | MAPTHSD17B10TSHRKMT2AMEN1 | |
| SCHEMBL2913875 | 0.77 | F10 (0.37) | MAPTHSD17B10TSHRALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2222646-A1 | URACIL OR THYMINE DERIVATIVE FOR TREATING HEPATITIS C | Abbott Laboratories (US) | 2010-09-01 | — | — | EP | disclosed |
| WO-2009039127-A1 | URACIL OR THYMINE DERIVATIVE FOR TREATING HEPATITIS C | ABBOTT LABORATORIES (US) | 2009-03-26 | — | — | WO | disclosed |