Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | KIF18A | Q8NI77 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | CFTR | P13569 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2910190 | 0.89 | GPR27 (0.42) | KMT2AMEN1 | |
| SCHEMBL2910683 | 0.88 | ALDH1A1 (0.36) | ITGA4L3MBTL1RAB9AALDH1A1BCL2L1 | |
| SCHEMBL2907832 | 0.88 | BCL2L1 (0.34) | ITGA4L3MBTL1KIF18ABCL2L1CFTR | |
| SCHEMBL2913154 | 0.88 | BCL2L1 (0.35) | ITGA4L3MBTL1KIF18ARAB9AALDH1A1 | |
| SCHEMBL2910962 | 0.88 | RAB9A (0.39) | L3MBTL1RAB9ANPC1SMN1; SMN2NPSR1 | |
| SCHEMBL2912963 | 0.88 | ALDH1A1 (0.42) | ITGA4L3MBTL1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL2914837 | 0.87 | KMT2A (0.41) | RAB9ANPC1SMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL2915315 | 0.87 | KIF18A (0.35) | ITGA4L3MBTL1KIF18ABCL2L1 | |
| SCHEMBL2907804 | 0.86 | XDH (0.39) | XDHATMITGA4L3MBTL1RAB9A | |
| SCHEMBL2915358 | 0.86 | ACLY (0.32) | NPC1NPSR1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2222646-A1 | URACIL OR THYMINE DERIVATIVE FOR TREATING HEPATITIS C | Abbott Laboratories (US) | 2010-09-01 | — | — | EP | disclosed |
| WO-2009039127-A1 | URACIL OR THYMINE DERIVATIVE FOR TREATING HEPATITIS C | ABBOTT LABORATORIES (US) | 2009-03-26 | — | — | WO | disclosed |