Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 1/20 | 0.46 |
| ▸ | CLK1 | P49759 | 3/20 | 0.45 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.45 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.45 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.45 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.41 |
| ▸ | FEN1 | P39748 | 1/20 | 0.41 |
| ▸ | LCK | P06239 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | JAK3 | P52333 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
| ▸ | DHFR | P00374 | 1/20 | 0.40 |
| ▸ | DUSP4 | Q13115 | 1/20 | 0.40 |
| ▸ | PTP4A1 | Q93096 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.39 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.39 |
| ▸ | PI4KA | P42356 | 1/20 | 0.39 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29509257 | 0.84 | LCK (0.50) | CLK1DYRK1ACSNK1DCSNK1ELCK | |
| SCHEMBL41506 | 0.84 | LCK (0.50) | CLK1DYRK1ACSNK1DCSNK1ELCK | |
| Hydrochloric Acid SCHEMBL29486326 | 0.82 | LCK (0.49) | CLK1DYRK1ACSNK1DCSNK1ELCK | |
| Hydrochloric Acid SCHEMBL3468306 | 0.82 | LCK (0.49) | CLK1DYRK1ACSNK1DCSNK1ELCK | |
| Hydrochloric Acid SCHEMBL28230152 | 0.82 | LCK (0.49) | CLK1DYRK1ACSNK1DCSNK1ELCK | |
| Biphenyl SCHEMBL28889831 | 0.81 | ADORA2A (0.51) | CLK1DYRK1ACSNK1DCSNK1ELCK | |
| Hydrochloric Acid SCHEMBL17237902 | 0.80 | LCK (0.47) | CLK1DYRK1ACSNK1DCSNK1ELCK | |
| SCHEMBL28802825 | 0.79 | CYP1A2 (0.54) | METAP2DUSP4PTP4A1CYP3A4EGFR | |
| SCHEMBL31418349 | 0.77 | RAB9A (0.55) | METAP2DUSP4PTP4A1CYP3A4CYP1A2 | |
| Quinoline SCHEMBL9745228 | 0.75 | ALDH1A1 (0.65) | METAP2DUSP4PTP4A1CYP3A4PIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115353507-B | Biphenyl pyrazine quinazoline diamine, synthesis, activity and application thereof | 首都医科大学 | 2023-10-20 | — | — | CN | disclosed |