Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.65 |
| ▸ | METAP2 | P50579 | 1/20 | 0.51 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.46 |
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | DUSP4 | Q13115 | 1/20 | 0.43 |
| ▸ | PTP4A1 | Q93096 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.41 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CASP7 | P55210 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Quinoline SCHEMBL29030603 | 0.93 | ALDH1A1 (0.57) | ALDH1A1METAP2CYP2A6EGFRNPC1 | |
| Quinoline SCHEMBL6568759 | 0.83 | ALDH1A1 (0.85) | ALDH1A1CYP2A6EGFRNPC1CYP3A4 | |
| Quinoline SCHEMBL28077521 | 0.83 | ALDH1A1 (0.85) | ALDH1A1CYP2A6EGFRNPC1CYP3A4 | |
| Quinoline SCHEMBL27752643 | 0.83 | ALDH1A1 (0.94) | ALDH1A1CYP2A6EGFRNPC1CYP3A4 | |
| Quinoline SCHEMBL27818244 | 0.83 | ALDH1A1 (0.94) | ALDH1A1CYP2A6EGFRNPC1CYP3A4 | |
| Quinoline SCHEMBL28008945 | 0.83 | ALDH1A1 (0.94) | ALDH1A1CYP2A6EGFRNPC1CYP3A4 | |
| Quinoline SCHEMBL27547943 | 0.83 | ALDH1A1 (0.94) | ALDH1A1CYP2A6EGFRNPC1CYP3A4 | |
| Quinoline SCHEMBL4831356 | 0.83 | ALDH1A1 (0.94) | ALDH1A1CYP2A6EGFRNPC1CYP3A4 | |
| SCHEMBL31418349 | 0.83 | RAB9A (0.55) | ALDH1A1METAP2NPC1DUSP4PTP4A1 | |
| Quinoline SCHEMBL28224950 | 0.81 | ALDH1A1 (0.90) | ALDH1A1CYP2A6EGFRNPC1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5141855-A | Forming cobalt complex of metallizable dye; analyte as reductant or producing reductant; spectrophotometric analysis of enzymes, blood, urine | EASTMAN KODAK COMPANY (US) | 1992-08-25 | — | — | US | disclosed |
| EP-0255089-A2 | Cobalt containing reagents and methods for the determination of analytes in aqueous fluids | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1988-02-03 | — | — | EP | disclosed |