Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.60 |
| ▸ | MEN1 | O00255 | 6/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.58 |
| ▸ | AHR | P35869 | 1/20 | 0.58 |
| ▸ | NPC1 | O15118 | 2/20 | 0.58 |
| ▸ | RAB9A | P51151 | 2/20 | 0.58 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.57 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.57 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.57 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | MAPT | P10636 | 5/20 | 0.56 |
| ▸ | TSHR | P16473 | 4/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | METAP2 | P50579 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | PNLIP | P16233 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13451640 | 0.79 | MEN1 (0.73) | MEN1KMT2AAHRNPC1RAB9A | |
| SCHEMBL6222503 | 0.77 | CFTR (0.54) | MAOBMEN1KMT2ANPC1RAB9A | |
| SCHEMBL516174 | 0.77 | KDM4E (0.53) | KMT2ANPC1RAB9AHDAC1HDAC8 | |
| SCHEMBL13665200 | 0.76 | MAPT (0.70) | MAOBMEN1KMT2ANPC1RAB9A | |
| SCHEMBL2183803 | 0.75 | PSEN1 (0.49) | HDAC1HDAC8HDAC6 | |
| SCHEMBL976167 | 0.75 | HDAC8 (0.59) | HDAC1HDAC8HDAC6HIF1AALDH1A1 | |
| SCHEMBL516118 | 0.75 | ALOX5 (0.52) | MAOBHDAC1HDAC8HDAC6ALDH1A1 | |
| SCHEMBL12501713 | 0.75 | KMT2A (0.78) | MAOBMEN1KMT2ANPC1RAB9A | |
| SCHEMBL679452 | 0.75 | CA12 (0.56) | MEN1KMT2ANPC1RAB9AHDAC1 | |
| SCHEMBL14825579 | 0.75 | ALOX5 (0.48) | MAOBMEN1KMT2AAHRNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116903493-A | Method for synthesizing polysubstituted o-phenylphenol compound through nucleophilic reaction ring opening of dibenzofuran | 华南理工大学 | 2023-10-20 | — | — | CN | disclosed |