Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 9/20 | 0.36 |
| ▸ | ESR1 | P03372 | 6/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.32 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.32 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8501660 | 0.86 | SLC18A3 (0.42) | TRPA1SLC18A3 | |
| SCHEMBL29266620 | 0.84 | TRPA1 (0.31) | TRPA1TRPM8 | |
| SCHEMBL1005980 | 0.82 | ESR2 (0.40) | ESR2ESR1 | |
| SCHEMBL5859418 | 0.78 | TRPA1 (0.31) | TRPA1TRPM8 | |
| SCHEMBL7597625 | 0.77 | TRPA1 (0.36) | TRPA1TRPM8 | |
| SCHEMBL8593394 | 0.76 | ESR2 (0.40) | ESR2ESR1 | |
| SCHEMBL16277193 | 0.73 | STS (0.32) | ESR2 | |
| SCHEMBL28494433 | 0.72 | SLC18A3 (0.39) | SLC18A3 | |
| SCHEMBL7113263 | 0.71 | SLC6A3 (0.41) | — | |
| SCHEMBL21724095 | 0.71 | SLC6A3 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103006543-A | Chilblain cream and preparation method thereof | SUZHOU HEIDOU SOFTWARE TECHNOLOGY CO LTD | 2013-04-03 | — | — | CN | disclosed |
| EP-2214630-A1 | PERSONAL CARE COMPOSITION | Unilever PLC (GB) | 2010-08-11 | — | — | EP | disclosed |
| WO-2009071422-A1 | PERSONAL CARE COMPOSITION | UNILEVER PLC (GB) | 2009-06-11 | — | — | WO | disclosed |
| US-5834445-A | PROVIDING A SUITABLE PASTEL COSMETIC COLOR BY COMBINING AN AQUEOUS SOLUTION OF A CYCLODEXTRIN, A TOPICAL CARRIER,AN ANTIOXIDANT AND AN ORGANIC SOLUTION OF B-CAROTENE; SKIN CREAMS | SIKORSKI CHRISTOPHER (US) | 1998-11-10 | — | — | US | disclosed |