Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.47 |
| ▸ | TUBB | P07437 | 1/20 | 0.47 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.47 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.47 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.47 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.47 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.47 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.47 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.47 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.47 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.47 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.47 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.47 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.47 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.47 |
| ▸ | SDHB | P21912 | 1/20 | 0.43 |
| ▸ | GSK3A | P49840 | 1/20 | 0.43 |
| ▸ | GSK3B | P49841 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29110282 | 0.86 | KDM4E (0.46) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL849309 | 0.86 | SYK (0.44) | MAPTGSK3AGSK3BTAS2R14NPC1 | |
| SCHEMBL30721208 | 0.86 | DHODH (0.53) | MAPTGSK3AGSK3BTAS2R14NPC1 | |
| SCHEMBL12984259 | 0.86 | DHODH (0.53) | MAPTGSK3AGSK3BTAS2R14NPC1 | |
| SCHEMBL12983920 | 0.84 | TUBB4A (0.41) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL22093021 | 0.83 | MAPK8 (0.51) | TAS2R14SYKLMNAMAPK8MAPK9 | |
| SCHEMBL17668102 | 0.83 | GAA (0.46) | MAPTTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL29417547 | 0.83 | NPC1 (0.43) | MAPTGSK3AGSK3BTAS2R14NPC1 | |
| SCHEMBL14575828 | 0.83 | NPC1 (0.43) | MAPTGSK3AGSK3BTAS2R14NPC1 | |
| SCHEMBL2437507 | 0.81 | TUBB4A (0.52) | MAPTTUBB4ATUBBTUBA3CTUBA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116903613-A | 2-oxo quinazoline five-membered heterocyclic derivative, preparation method and application thereof | 深圳微芯生物科技股份有限公司 | 2023-10-20 | — | — | CN | disclosed |